Document Detail

Relation of prognosis in sick sinus syndrome to age, conduction defects and modes of permanent cardiac pacing.
MedLine Citation:
PMID:  2316455     Owner:  NLM     Status:  MEDLINE    
A large population of sick sinus syndrome (SSS) patients was analyzed to determine whether age of patients, presence of conduction disturbances and mode of permanent pacing are related to the occurrence of supraventricular tachyarrhythmias, cerebral embolism and cardiac mortality. Three hundred thirty-nine patients permanently paced (135 AAI, 79 DDD, 125 VVI) because of SSS were followed for a mean period of 5 years (range 2 to 10). Patients were divided into 4 groups according to age (less than 70 or greater than 70 years) and the presence or absence of an associated conduction disturbance. Sixty-eight percent of VVI, 55% of AAI and 40.5% of DDD patients were greater than 70 years of age. In the VVI and DDD groups a conduction disturbance was present in 67 of 204 (33%) patients; conduction disturbances were more common in patients greater than 70 years old (46 of 111, 41%) than in those less than 70 years old (21 of 93,22%). The Wenckebach threshold (greater than 140 beats/min) remained unchanged during the follow-up period in 82% of AAI patients. In 9% of these patients, the Wenckebach threshold showed some degree of deterioration, but only in 2 patients was it less than 100 beats/min (1.5%). Spontaneous second-degree atrioventricular block was observed in 7 patients (5%); it disappeared in 6 of these patients when drug therapy was discontinued.(ABSTRACT TRUNCATED AT 250 WORDS)
M Santini; G Alexidou; G Ansalone; G Cacciatore; R Cini; G Turitto
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  The American journal of cardiology     Volume:  65     ISSN:  0002-9149     ISO Abbreviation:  Am. J. Cardiol.     Publication Date:  1990 Mar 
Date Detail:
Created Date:  1990-04-20     Completed Date:  1990-04-20     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0207277     Medline TA:  Am J Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  729-35     Citation Subset:  AIM; IM    
Electrophysiology Laboratory and Pacemaker Center, S. Camillo Hospital, Rome, Italy.
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MeSH Terms
Age Factors
Atrial Fibrillation / etiology
Cardiac Pacing, Artificial / methods
Cerebrovascular Disorders / etiology
Follow-Up Studies
Heart Block / etiology
Middle Aged
Pacemaker, Artificial*
Sick Sinus Syndrome / complications,  mortality*,  therapy
Tachycardia, Supraventricular / etiology
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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