| Relation of physical activity, cardiac function, exercise capacity, and quality of life in patients with a systemic right ventricle. | |
| | |
MedLine Citation:
|
PMID: 18940303 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Exercise is recommended in patients with left ventricular failure. Although right ventricular failure is common in patients with a systemic right ventricle (RV), no data are available on the effect of physical activity in these patients. The aim of this study was to evaluate the relation of physical activity and cardiac function, exercise capacity, and quality of life in patients with a systemic RV. Forty-seven patients (64% men, mean age 35 years, range 21 to 69) with a systemic RV (31 with an atrially switched transposition of the great arteries and 16 with a congenitally corrected transposition of the great arteries) were included. Cardiac function was assessed by cardiovascular magnetic resonance or computed tomography, exercise tests, and serum N-terminal prohormone brain natriuretic peptide (NT-pro-BNP) levels. Habitual physical activity was assessed using the Short Questionnaire to Assess Health-Enhancing Physical Activity (SQUASH) and quality of life using the Medical Outcomes Study Short Form 36-Item Health Survey. Mean systemic right ventricular ejection fraction was impaired (36.8 +/- 7.8%), as was maximal exercise capacity (78.5 +/- 23.9% of predicted). NT-pro-BNP level was increased (median 269 ng/L, range 34 to 4,476). Mean SQUASH score was 6,808 +/- 3,241, indicating a decreased level of habitual physical activity. Although patients' scores on mental quality-of-life domains were comparable to the general population, scores on most physical quality-of-life domains were significantly lower. SQUASH scores were found to be a significant predictor for exercise capacity (p <0.01) and physical quality of life (p <0.001). However, we found no relation between SQUASH scores and right ventricular ejection fraction or NT-pro-BNP. In conclusion, physical activity in patients with a systemic RV is positively associated with exercise capacity and quality of life, irrespective of cardiac performance. |
| | |
Authors:
|
Michiel M Winter; Berto J Bouma; Arie P J van Dijk; Maarten Groenink; Pythia T Nieuwkerk; Mart N van der Plas; Gertjan T Sieswerda; Thelma C Konings; Barbara J M Mulder |
Related Documents
:
|
15948103 - Can exercise-induced changes in b-type natriuretic peptides be used to detect cardiac i... 10908083 - Plasma norepinephrine and atrial natriuretic peptide in heart failure: influence of fel... 12852673 - Functional dystonia in musicians: rehabilitation. |
Publication Detail:
|
Type: Comparative Study; Journal Article Date: 2008-08-27 |
Journal Detail:
|
Title: The American journal of cardiology Volume: 102 ISSN: 1879-1913 ISO Abbreviation: Am. J. Cardiol. Publication Date: 2008 Nov |
Date Detail:
|
Created Date: 2008-10-22 Completed Date: 2009-01-06 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0207277 Medline TA: Am J Cardiol Country: United States |
Other Details:
|
Languages: eng Pagination: 1258-62 Citation Subset: AIM; IM |
Affiliation:
|
Department of Cardiology, Academic Medical Center, Amsterdam, The Netherlands. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Aged Exercise Test Exercise Tolerance* Female Heart Failure / blood, diagnosis*, physiopathology* Heart Ventricles / physiopathology Humans Magnetic Resonance Imaging Male Middle Aged Motor Activity* Natriuretic Peptide, Brain / blood Peptide Fragments / blood Quality of Life* Stroke Volume Tomography, X-Ray Computed Transposition of Great Vessels / surgery* Ventricular Dysfunction, Right / physiopathology |
| Chemical | |
Reg. No./Substance:
|
0/Peptide Fragments; 0/pro-brain natriuretic peptide (1-76); 114471-18-0/Natriuretic Peptide, Brain |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Comparison of clinical features of arrhythmogenic right ventricular cardiomyopathy in men versus wom...
Next Document: Physical activity during daily life and circulating biomarker levels in patients with peripheral art...