Document Detail

Relation of parental history of coronary heart disease to obesity in young adults.
MedLine Citation:
PMID:  12629564     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To assess the association between obesity and parental coronary heart disease (CHD) history.
DESIGN: Analysis of data from an ongoing, large-scale survey on medical status, health behaviour and attitudes.
SUBJECTS: Representative samples of Israeli military personnel upon discharge from compulsory service at age 20-22 y. Overall 14297 men and 11638 women were interviewed and examined upon release from military service between 1989 and 1999.
MEASUREMENTS: Data on demographic characteristics, family history of CHD, lifestyle, weight and height were collected. Analysis of variance and logistic regression were used.
RESULTS: Higher mean body mass index (BMI) and obesity (BMI>30 kg/m(2)) were associated with paternal CHD history in both sexes, and with maternal CHD history among men. Offspring of a parent with a positive CHD history had a higher mean BMI (23.22 vs 22.86 kg/m(2), P<0.001) and were more likely to be obese (5.4 vs 3.7%, P<0.001) than offspring of parents with no history of CHD. Multivariate adjustment for demographic and behavioural variables associated with obesity attenuated the association (adjusted odds ratio for obesity 1.37, 95% confidence interval: 1.15, 1.64). When stratified by sex, this association remained statistically significant only among males.
CONCLUSION: Young adults with a parental history of CHD are more likely to be overweight. This high-risk group should be targeted for early preventive activities.
I Grotto; M Huerta; J D Kark; O Shpilberg; J Meyerovitch
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity     Volume:  27     ISSN:  -     ISO Abbreviation:  Int. J. Obes. Relat. Metab. Disord.     Publication Date:  2003 Mar 
Date Detail:
Created Date:  2003-03-11     Completed Date:  2003-04-17     Revised Date:  2014-06-03    
Medline Journal Info:
Nlm Unique ID:  9313169     Medline TA:  Int J Obes Relat Metab Disord     Country:  England    
Other Details:
Languages:  eng     Pagination:  362-8     Citation Subset:  IM    
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MeSH Terms
Analysis of Variance
Body Mass Index
Coronary Disease / etiology,  genetics*
Health Surveys
Israel / epidemiology
Logistic Models
Obesity / complications,  epidemiology,  genetics*
Odds Ratio
Risk Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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