| Relation of gastric distention to prostaglandin therapy in neonates. | |
| | |
MedLine Citation:
|
PMID: 9122396 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
PURPOSE: To evaluate the short-term gastric effects of prostaglandin therapy in neonates. MATERIALS AND METHODS: The authors retrospectively reviewed the radiographs of nine neonates with congenital heart disease who received prostaglandins during the 1st week of life. Eighteen matched control infants (nine healthy neonates and nine infants with noncyanotic congenital heart disease) who did not receive prostaglandins were also evaluated. RESULTS: Within 48 hours of initial prostaglandin therapy, persistent (>3 days) gastric distention was noted in four of nine infants. No infants developed feeding intolerance during the 1st week of life; two of nine infants (both with initial asymptomatic gastric distention) developed feeding intolerance with prolonged prostaglandin therapy. In all cases, gastric distention resolved with cessation of prostaglandins. The radiographs of the control infants were unremarkable (P < .01). CONCLUSION: Persistent, asymptomatic gastric distention can be seen in neonates within 48 hours of initiation of prostaglandin therapy. Intervention is not warranted; this finding resolves with cessation of prostaglandins. Early gastric distention may be predictive of feeding intolerance in infants who receive prolonged prostaglandin therapy. |
| | |
Authors:
|
V M Kriss; N S Desai |
Related Documents
:
|
10755456 - Respiratory sinus arrhythmia during feeding: a measure of vagal regulation of metabolis... 12614946 - Maternal infant bonding enhanced after atrial septostomy in cyanotic neonates in a gene... 12278626 - Observations on nutritional marasmus in a newly rich nation. 22875746 - Study of stillbirth and major congenital anomaly among newborns in the high-level natur... 9749326 - Mortality in vietnam, 1979-1989. 11158516 - Brain auditory activation measured by near-infrared spectroscopy (nirs) in neonates. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Radiology Volume: 203 ISSN: 0033-8419 ISO Abbreviation: Radiology Publication Date: 1997 Apr |
Date Detail:
|
Created Date: 1997-04-22 Completed Date: 1997-04-22 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 0401260 Medline TA: Radiology Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 219-21 Citation Subset: AIM; IM |
Affiliation:
|
Department of Diagnostic Radiology, University of Kentucky, Lexington 40536-0084, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Alprostadil
/
adverse effects*,
therapeutic use Heart Defects, Congenital / drug therapy Humans Infant, Newborn Retrospective Studies Stomach / drug effects*, radiography |
| Chemical | |
Reg. No./Substance:
|
745-65-3/Alprostadil |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: First-trimester US parameters of failed pregnancy.
Next Document: Lower urinary tract abnormalities in children with multicystic dysplastic kidney.