Document Detail

Relation of exercise-induced physiologic S-T segment depression to R wave amplitude in normal subjects.
MedLine Citation:
PMID:  7435387     Owner:  NLM     Status:  MEDLINE    
Exercise electrocardiography was performed in 100 asymptomatic male volunteers with a mean age of 42.6 years. The R wave and total RS amplitude and the magnitude of physiologic S-T segment depression at the J junction were quantitated for a modified bipolar CC5 lead and a vertically oriented bipolar lead (VL) using computer-averaged groups of 25 consecutive QRS complexes from each of seven stages of rest and exercise. Computer-generated X-Y plots were used to examine the correlations between the magnitude of S-T depression and the R wave and total RS amplitudes. The magnitude of S-T depression and of the R wave amplitude were unrelated at standing rest but showed increasing correlation with progressive increases in exercise heart rate (correlation coefficient = 0.425, p < 0.00001 at maximal exercise). The total RS amplitude was also related to the magnitude of S-T depression during exercise, but the correlations did not improve progressively with increases in exercise heart rate. The magnitude of S-T depression was more closely related to R wave amplitude and total RS amplitude in the vertically oriented lead than in the CC5 lead. These data demonstrate a significant relation between the magnitude of R wave and total RS amplitudes and the magnitude of physiologic S-T segment depression in normal subjects during exercise. They suggest the need for evaluation of S-T depression corrected for R wave amplitude in an attempt to improve the diagnostic accuracy of the exercise electrocardiogram. The data also suggest that the criteria for abnormal S-T depression should take into consideration the different R wave voltages reflected by different types of recording leads.
M C Gerson; S N Morris; P L McHenry
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  The American journal of cardiology     Volume:  46     ISSN:  0002-9149     ISO Abbreviation:  Am. J. Cardiol.     Publication Date:  1980 Nov 
Date Detail:
Created Date:  1981-01-26     Completed Date:  1981-01-26     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0207277     Medline TA:  Am J Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  778-82     Citation Subset:  AIM; IM    
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MeSH Terms
Exercise Test
Heart Rate
Middle Aged
Grant Support

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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