| Relation of exercise-induced physiologic S-T segment depression to R wave amplitude in normal subjects. | |
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MedLine Citation:
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PMID: 7435387 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Exercise electrocardiography was performed in 100 asymptomatic male volunteers with a mean age of 42.6 years. The R wave and total RS amplitude and the magnitude of physiologic S-T segment depression at the J junction were quantitated for a modified bipolar CC5 lead and a vertically oriented bipolar lead (VL) using computer-averaged groups of 25 consecutive QRS complexes from each of seven stages of rest and exercise. Computer-generated X-Y plots were used to examine the correlations between the magnitude of S-T depression and the R wave and total RS amplitudes. The magnitude of S-T depression and of the R wave amplitude were unrelated at standing rest but showed increasing correlation with progressive increases in exercise heart rate (correlation coefficient = 0.425, p < 0.00001 at maximal exercise). The total RS amplitude was also related to the magnitude of S-T depression during exercise, but the correlations did not improve progressively with increases in exercise heart rate. The magnitude of S-T depression was more closely related to R wave amplitude and total RS amplitude in the vertically oriented lead than in the CC5 lead. These data demonstrate a significant relation between the magnitude of R wave and total RS amplitudes and the magnitude of physiologic S-T segment depression in normal subjects during exercise. They suggest the need for evaluation of S-T depression corrected for R wave amplitude in an attempt to improve the diagnostic accuracy of the exercise electrocardiogram. The data also suggest that the criteria for abnormal S-T depression should take into consideration the different R wave voltages reflected by different types of recording leads. |
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Authors:
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M C Gerson; S N Morris; P L McHenry |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: The American journal of cardiology Volume: 46 ISSN: 0002-9149 ISO Abbreviation: Am. J. Cardiol. Publication Date: 1980 Nov |
Date Detail:
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Created Date: 1981-01-26 Completed Date: 1981-01-26 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0207277 Medline TA: Am J Cardiol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 778-82 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Electrocardiography* Exercise Test Heart Rate Humans Male Middle Aged Rest |
| Grant Support | |
ID/Acronym/Agency:
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HL-06308/HL/NHLBI NIH HHS; HL-07182/HL/NHLBI NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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