Document Detail


Relation of change in wall motion and glucose metabolism after coronary artery bypass grafting--assessment with positron emission tomography.
MedLine Citation:
PMID:  1942498     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Regional myocardial glucose metabolism was assessed by positron emission tomography (PET) in stunned myocardium. PET perfusion and metabolic imaging using N-13 ammonia and F-18 deoxyglucose (FDG) was performed before and 5-7 weeks after coronary artery bypass grafting (CABG) in 23 patients with coronary artery disease. Of 22 asynergy segments showing increased FDG uptake preoperatively, the postoperative PET showed a decrease in FDG uptake in 16 segments (73%) and persistent uptake in 6 segments (27%). The improvement in asynergy was observed in all of the segments showing postoperative decrease in FDG uptake, while it was observed in only 50% of those with persistent FDG uptake (p less than 0.01). On the other hand, 4 of 5 segments showing a new FDG uptake postoperatively revealed deterioration of wall motion abnormality. These data suggest that an increase in exogenous glucose utilization may often persist in postischemic myocardium. Improvement in regional function seems to be associated with the improvement in metabolic abnormality after CABG.
Authors:
N Tamaki; Y Yonekura; K Yamashita; Y Magata; K Hirata; T Ban; J Konishi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Japanese circulation journal     Volume:  55     ISSN:  0047-1828     ISO Abbreviation:  Jpn. Circ. J.     Publication Date:  1991 Sep 
Date Detail:
Created Date:  1991-12-06     Completed Date:  1991-12-06     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7806868     Medline TA:  Jpn Circ J     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  923-9     Citation Subset:  IM    
Affiliation:
Department of Radiology & Nuclear Medicine, Kyoto University Faculty of Medicine, Japan.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Coronary Artery Bypass*
Coronary Disease / physiopathology,  radionuclide imaging,  surgery
Female
Glucose / metabolism*
Heart / radionuclide imaging*
Humans
Male
Middle Aged
Myocardial Contraction*
Myocardium / metabolism*
Tomography, Emission-Computed
Chemical
Reg. No./Substance:
50-99-7/Glucose

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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