| RELATION BETWEEN TRUNK FAT VOLUME AND REDUCTION OF TOTAL LUNG CAPACITY IN OBESE MEN. | |
| | |
MedLine Citation:
|
PMID: 21940844 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
Reduction in total lung capacity(TLC) in obese men is associated with restricted expansion of the thoracic cavity at full inflation. We hypothesised that thoracic expansion was reduced by the load imposed by increased total trunk fat volume or its distribution. Using magnetic resonance imaging(MRI) we measured internal and subcutaneous trunk fat and total abdominal and thoracic volumes at full inflation in 14 obese men(mean 52.4yrs, BMI 38.6(range 36-44)kg.m(-2) and 7 control men(mean 50.1yrs, BMI 25.0(range 22-27.5)kg.m(-2). TLC was measured by multibreath helium dilution and was restricted(<80%pred) in 6 obese men(OR). All measurements were made with subjects supine. Mean total trunk fat volume was 16.65(range 12.6-21.8)L in obese men and 6.98(range 3.0-10.8)L in control men. Anthropometry and mean total trunk fat volumes were similar in OR men and obese men without restriction(ON). Mean total intra-abdominal volume was 9.41L in OR and 11.15L in ON men. In obese men reduced thoracic expansion at full inflation and restriction of TLC were not inversely related to a large volume of a)intra-abdominal or total abdominal fat, b)subcutaneous fat volume around the thorax, or c)total trunk fat volume. In addition trunk fat volumes in obese men were not inversely related to gas volume or estimated intra-thoracic volume at supine functional residual capacity. In conclusion this study failed to support the hypotheses that restriction of TLC or impaired expansion of the thorax at full inflation in middle-aged obese men was simply a consequence of a large abdominal volume or total trunk fat volume or its distribution. |
| | |
Authors:
|
R A Watson; Neil B Pride; E Louise Thomas; P W Ind; Jimmy D Bell |
Related Documents
:
|
10480074 - Managing diet quality for cheddar cheese manufacturing milk. 1. the influence of protei... 11400474 - Characterization and fat migration of palm kernel stearin as affected by addition of de... 6643314 - Characterization of straightbred and crossbred rabbits for milk production and associat... 11694044 - Development and application of confocal scanning laser microscopy methods for studying ... 10098504 - Role of the vagus nerve in mediating proximal nutrient-induced glucagon-like peptide-1 ... 6882504 - Anti-proliferative effect of pyridinolcarbamate and of aspirin in the early stages of a... |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-9-22 |
Journal Detail:
|
Title: Journal of applied physiology (Bethesda, Md. : 1985) Volume: - ISSN: 1522-1601 ISO Abbreviation: - Publication Date: 2011 Sep |
Date Detail:
|
Created Date: 2011-9-23 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8502536 Medline TA: J Appl Physiol Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
|
1Imperial College. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Chronic Kidney Disease and Albuminuria in Children with Sickle Cell Disease.
Next Document: Functional effect of longitudinal heterogeneity in constricted airways before and after lung expansi...