| Relation between successful late coronary angioplasty of an occluded, infarction-related artery and lower prevalence of ventricular late potentials. | |
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MedLine Citation:
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PMID: 9647414 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: The effect of mechanical reperfusion of the infarction-related artery on ventricular late potentials (VLP) continues to be debated. OBJECTIVE: To assess the influence of successful late coronary angioplasty on the prevalence of VLP after acute myocardial infarction (AMI). METHODS: We studied 113 consecutive patients (97 men, 16 women, mean age 57 +/- 10.8 years) in whom the infarction-related artery was occluded (thrombolysis in myocardial infarction score 0 or 1) at the time of the initial coronary arteriography 10.9 +/- 6.4 days after a first AMI. Successful late angioplasty of the infarcted artery was performed in 55 patients a mean of 11.5 +/- 7.2 days after AMI. The remaining 58 patients received a conservative treatment. Signal-averaged electrocardiograms (SAECGs) were recorded 25 +/- 10.2 days after AMI. Multivariate analysis was undertaken to assess the influence of late coronary angioplasty with respect to age, sex, infarction site, angiographic ejection fraction, extent of diseased coronary arteries, thrombolysis and time of recording the SAECG. RESULTS: The overall prevalence of VLP was 27%. It was greater in patients without than in those with angioplasty (40% compared with 15%, P = 0.017). Multivariate analysis demonstrated that successful angioplasty (odds ratio 3.2; P = 0.019) and ejection fraction >0.4 (odds ratio 5.1; P = 0.0051) were the strongest independent predictors of an absence of VLP. 'Non-inferior' myocardial infarction was also correlated with the absence of VLP (odds ratio 2.6), but with borderline significance (P = 0.053). CONCLUSION: When performed in an occluded, infarction-related artery, successful late coronary angioplasty contributes to a significant decrease in the prevalence of VLP. |
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Authors:
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E Lomama; G Helft; A Persoz; A Vacheron |
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Publication Detail:
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Type: Clinical Trial; Comparative Study; Controlled Clinical Trial; Journal Article |
Journal Detail:
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Title: Coronary artery disease Volume: 9 ISSN: 0954-6928 ISO Abbreviation: Coron. Artery Dis. Publication Date: 1998 |
Date Detail:
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Created Date: 1998-09-04 Completed Date: 1998-09-04 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9011445 Medline TA: Coron Artery Dis Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 125-9 Citation Subset: IM |
Affiliation:
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Division of Cardiology and Cardiovascular Rehabilitation, Centre Médical des Pins, Lamotte-Beuvron, France. |
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Angioplasty, Transluminal, Percutaneous Coronary* / adverse effects Electrocardiography* Female Follow-Up Studies Humans Logistic Models Male Middle Aged Multivariate Analysis Myocardial Infarction / complications, therapy* Prevalence Signal Processing, Computer-Assisted Ventricular Dysfunction, Left / diagnosis, epidemiology*, etiology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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