Document Detail

Relation between periventricular haemorrhage and ischaemic brain lesions diagnosed by ultrasound in very pre-term infants.
MedLine Citation:
PMID:  2865617     Owner:  NLM     Status:  MEDLINE    
Ultrasound brain scans were carried out serially during the first month of life on 219 newborn infants of 32 weeks' gestation or less. Periventricular haemorrhage (PVH) alone was observed in 36.1% and ischaemic lesions in 17.8%. By comparison with PVH, ischaemic lesions evolved later (median 7 days vs 2 days), and were associated with a significantly higher frequency of persistent ventricular enlargement and increased mortality. Birth asphyxia, antepartum haemorrhage, recurrent apnoea, and septicaemia--events which are known to promote systemic hypotension--were all strongly associated with ischaemic lesions but not with PVH alone.
S K Sinha; J M Davies; D G Sims; M L Chiswick
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Lancet     Volume:  2     ISSN:  0140-6736     ISO Abbreviation:  Lancet     Publication Date:  1985 Nov 
Date Detail:
Created Date:  1985-12-18     Completed Date:  1985-12-18     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  2985213R     Medline TA:  Lancet     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  1154-6     Citation Subset:  AIM; IM    
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MeSH Terms
Brain Ischemia / complications*,  diagnosis,  mortality
Cerebral Hemorrhage / complications*,  diagnosis,  mortality
Cerebral Ventricles / pathology
Dilatation, Pathologic / etiology
Infant, Newborn
Infant, Premature, Diseases / complications*,  diagnosis,  mortality

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