Document Detail


Relation between mouth and haematogenous infection in total joint replacements.
MedLine Citation:
PMID:  8086903     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To investigate the source of infections associated with orthopaedic prostheses. DESIGN: Analysis of four infections of prosthetic joints with case records; minimum inhibitory and minimum bactericidal concentrations and sodium dodecylsulphate polyacrylamide gel electrophoresis of the cell wall polypeptides of the Streptococcus sanguis isolates from the mouth and infected prostheses; examination of the patients' mouths for periodontal disease and caries. SUBJECTS: Four adults (three men) aged 58-83. RESULTS: For each patient the strain of S sanguis isolated from the mouth was indistinguishable from that isolated from the prosthesis. All patients had severe periodontal disease and caries. CONCLUSIONS: The mouth was probably the source of bacterial infection in the prosthetic joints of these patients; the route of infection was possibly haematogenous. Incipient oral infection should be treated before joint replacement, and oral health should be maintained indefinitely.
Authors:
C A Bartzokas; R Johnson; M Jane; M V Martin; P K Pearce; Y Saw
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  BMJ (Clinical research ed.)     Volume:  309     ISSN:  0959-8138     ISO Abbreviation:  BMJ     Publication Date:    1994 Aug 20-27
Date Detail:
Created Date:  1994-10-20     Completed Date:  1994-10-20     Revised Date:  2010-03-24    
Medline Journal Info:
Nlm Unique ID:  8900488     Medline TA:  BMJ     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  506-8     Citation Subset:  AIM; IM    
Affiliation:
Wirral Hospital NHS Trust, Wirral, Merseyside.
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MeSH Terms
Descriptor/Qualifier:
Aged
Aged, 80 and over
Bacterial Typing Techniques
Electrophoresis, Polyacrylamide Gel
Female
Hip Prosthesis
Humans
Joint Prosthesis*
Knee Prosthesis
Male
Microbial Sensitivity Tests
Middle Aged
Mouth / microbiology*
Periodontal Diseases / microbiology
Prosthesis-Related Infections / microbiology*,  transmission
Streptococcal Infections / microbiology*,  transmission
Streptococcus sanguis / isolation & purification*
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