| Relation between estimates of cornstarch digestibility by the Englyst in vitro method and glycemic response, subjective appetite, and short-term food intake in young men. | |
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MedLine Citation:
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PMID: 20164321 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Starch composition and rate of digestion are determinants of blood glucose concentrations and food intake (FI). OBJECTIVE: Our objective was to describe relations between estimates of digestibility of starches by the in vitro Englyst method and their effect on blood glucose concentrations, subjective appetite, and FI in young men. DESIGN: Subjects consumed 5 soups containing 50 g maltodextrin, whole-grain, high-amylose, regular cornstarch, or no added starch at 1-wk intervals. Ad libitum FI was measured at 30 min (experiment 1) or 120 min (experiment 2) later, which were the estimated times of digestion of a rapidly digestible starch (RDS) and slowly digestible starch, respectively. Blood glucose concentrations and appetite were measured pre- and postmeal. RESULTS: At 30 min, FI was reduced by maltodextrin only [86% RDS, 12% resistant starch (RS); P < 0.05], but at 120 min FI was reduced by whole-grain (24% RDS, 66% RS), high-amylose corn (40% RDS, 48% RS), and regular corn (27% RDS, 39% RS) (P < 0.0001). The premeal blood glucose concentration at 30 and 120 min was highest and lowest after maltodextrin treatment, respectively (P < 0.0001). After the meal, the blood glucose area under the curve at 30 min was lower after all starch treatments (P < 0.05), but at 120 min the blood glucose area under the curve was lower only after the regular cornstarch treatment (P < 0.05). Premeal appetite decreased by all treatments (P < 0.05). CONCLUSION: The in vitro estimates of starch digestibility by the Englyst method predicted the effects of starch composition on blood glucose concentrations and FI in young men 30 and 120 min after consumption. This trial was registered at clinicaltrials.gov as NCT00980941 for experiment 1 and NCT00988689 for experiment 2. |
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Authors:
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G Harvey Anderson; Clara E Cho; Tina Akhavan; Rebecca C Mollard; Bohdan L Luhovyy; E Terry Finocchiaro |
Publication Detail:
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Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't Date: 2010-02-17 |
Journal Detail:
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Title: The American journal of clinical nutrition Volume: 91 ISSN: 1938-3207 ISO Abbreviation: Am. J. Clin. Nutr. Publication Date: 2010 Apr |
Date Detail:
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Created Date: 2010-03-22 Completed Date: 2010-04-07 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0376027 Medline TA: Am J Clin Nutr Country: United States |
Other Details:
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Languages: eng Pagination: 932-9 Citation Subset: AIM; IM |
Affiliation:
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Department of Nutritional Sciences, Faculty of Medicine, University of Toronto, Toronto, Canada. harveyanderson@utoronto.ca |
| Data Bank Information | |
Bank Name/Acc. No.:
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ClinicalTrials.gov/NCT00980941; NCT00988689 |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Amylose / metabolism, pharmacology Appetite / drug effects* Area Under Curve Biological Availability Blood Glucose / metabolism* Dietary Carbohydrates / metabolism, pharmacology* Digestion Energy Intake* Food Analysis Glycemic Index Humans Male Polysaccharides / metabolism, pharmacology Satiety Response / drug effects Seeds Starch / metabolism, pharmacology* Young Adult Zea mays |
| Chemical | |
Reg. No./Substance:
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0/Blood Glucose; 0/Dietary Carbohydrates; 0/Polysaccharides; 9005-25-8/Starch; 9005-82-7/Amylose; 9050-36-6/maltodextrin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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