Document Detail


Relation between body size and bone mineral density in elderly men and women.
MedLine Citation:
PMID:  8356959     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This cross-sectional study of the Rancho Bernardo, California, cohort examines the relation between bone mineral density and eight measures of body size (total weight, body mass index, waist-hip ratio, lean mass, fat mass, percentage fat mass, and current and maximum adult height) measured between 1988 and 1991 in 1,492 ambulatory white adults aged 55-84 years. Lean mass, fat mass, and percentage fat mass were measured by bioelectric impedance. Bone mineral density was measured at the hip and lumbar spine with dual-energy x-ray absorptiometry and at the midshaft and ultradistal radius with single photon absorptiometry. In multiple linear regression models adjusted for age, smoking, exercise, alcohol, thiazide use, and estrogen use (in women), total weight was the most consistent marker of bone mineral density overall. In this cohort, all measures of body size were associated with bone mineral density in both sexes and were better markers of bone mineral density in the weight-bearing sites than in the non-weight-bearing sites, implying a mechanical effect of weight on bone mineral density.
Authors:
S L Edelstein; E Barrett-Connor
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  American journal of epidemiology     Volume:  138     ISSN:  0002-9262     ISO Abbreviation:  Am. J. Epidemiol.     Publication Date:  1993 Aug 
Date Detail:
Created Date:  1993-09-23     Completed Date:  1993-09-23     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7910653     Medline TA:  Am J Epidemiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  160-9     Citation Subset:  IM    
Affiliation:
Department of Family and Preventive Medicine, University of California, San Diego, La Jolla 92093-0607.
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MeSH Terms
Descriptor/Qualifier:
Absorptiometry, Photon
Aged
Aged, 80 and over
Aging / physiology*
Anthropometry
Body Constitution*
Body Mass Index
Body Weight
Bone Density*
Cross-Sectional Studies
Female
Femur Neck / metabolism
Humans
Lumbar Vertebrae / metabolism
Male
Middle Aged
Radius / metabolism
Grant Support
ID/Acronym/Agency:
AG 07181/AG/NIA NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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