Document Detail


Relation between blood flow and morphology in islet organ of rat pancreas.
MedLine Citation:
PMID:  2409813     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
By intra-arterial postmortem staining of the pancreas with hematoxylin after the administration of nonradioactive microspheres to anesthetized unfasted rats, the following values (+/-SE) were obtained: mean single islet volume, 1.00 +/- 0.12 nl (median 0.32 +/- 0.04 nl, n = 14); pancreatic intensity of perfusion, 1.18 +/- 0.14 ml X min-1 X g-1 (n = 10); percentage of pancreatic flow to islets, 6 +/- 1% (n = 10); single islet blood flow, 20 +/- 3 ml X min-1 (n = 10); and islet perfusion, 19 +/- 3 ml X min-1 X g-1 (n = 10). Perfusion of islet tissue was calculated to be above average for very small islets and to decrease with increasing islet size to become below average for very large ones. Details of the distribution of the total islet flow to subpopulations of islets grouped according to single islet size are shown pictorially.
Authors:
N Lifson; C V Lassa; P K Dixit
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  The American journal of physiology     Volume:  249     ISSN:  0002-9513     ISO Abbreviation:  Am. J. Physiol.     Publication Date:  1985 Jul 
Date Detail:
Created Date:  1985-08-12     Completed Date:  1985-08-12     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0370511     Medline TA:  Am J Physiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  E43-8     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Islets of Langerhans / anatomy & histology,  blood supply*
Male
Microspheres
Pancreas / anatomy & histology,  blood supply
Rats
Regional Blood Flow
Staining and Labeling
Grant Support
ID/Acronym/Agency:
AM-25697/AM/NIADDK NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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