Document Detail


Relation between acute ventricular arrhythmias, ventricular late potentials and mortality in acute myocardial infarction.
MedLine Citation:
PMID:  1746419     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The relation between ventricular late potentials and the occurrence of acute (in-hospital) and hyperacute (before hospital admission) ventricular tachycardia or fibrillation was studied in 281 consecutive patients with uninterrupted acute myocardial infarction. The prevalence of late potentials was significantly higher in patients with than without ventricular tachycardia/fibrillation (65 vs 22%; p less than 0.01). These relations persisted among patients with left bundle branch block, although a different definition was used for identifying late potentials in these patients. Multivariate analysis showed that presence of late potentials and peak creatine kinase enzyme level were the only 2 independent variables associated with early ventricular tachycardia/fibrillation. Total in-hospital mortality, as well as in-hospital cardiac mortality, was significantly higher among patients with than without acute ventricular tachycardia/fibrillation. However, at 1 year, mortality rates did not differ between the 2 groups. The following conclusions were drawn from this study: (1) Late potentials are closely related to ventricular tachycardia/fibrillation in hyperacute and acute phases of infarction. (2) Presence of left bundle branch block does not mitigate against the finding of late potentials in these patients. (3) Early ventricular tachycardia/fibrillation in acute infarction is related to large infarctions and to a high in-hospital mortality rate.
Authors:
M Hong; T Peter; W Peters; F Z Wang; Y X Xiu; C Vaughn; E S Gang
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The American journal of cardiology     Volume:  68     ISSN:  0002-9149     ISO Abbreviation:  Am. J. Cardiol.     Publication Date:  1991 Dec 
Date Detail:
Created Date:  1992-01-10     Completed Date:  1992-01-10     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0207277     Medline TA:  Am J Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1403-9     Citation Subset:  AIM; IM    
Affiliation:
Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California 90048.
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MeSH Terms
Descriptor/Qualifier:
Aged
Aged, 80 and over
Bundle-Branch Block / complications
Chi-Square Distribution
Electrocardiography / methods
Female
Humans
Logistic Models
Male
Middle Aged
Multivariate Analysis
Myocardial Infarction / complications*,  mortality*,  physiopathology
Prospective Studies
Signal Processing, Computer-Assisted
Tachycardia / complications*,  mortality,  physiopathology
Ventricular Fibrillation / complications*,  mortality,  physiopathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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