| Relation of left ventricular twist and global strain with right ventricular dysfunction in patients after operative "correction" of tetralogy of fallot. | |
| | |
MedLine Citation:
|
PMID: 20723653 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
In patients with corrected tetralogy of Fallot (cToF), left ventricular (LV) dysfunction is closely related to right ventricular (RV) dysfunction, indicating adverse ventricular-ventricular interactions. However, the mechanism that links RV dysfunction to LV dysfunction remains unclear. In this prospective study, 32 patients with cToF and 19 controls were enrolled. With cardiac magnetic resonance imaging, biventricular ejection fractions were assessed. Using 2-dimensional speckle tracking, global and regional RV and LV strains and LV twist were assessed. To detect and characterize ventricular-ventricular interaction, the relation between global and regional RV mechanics and global and regional LV mechanics was assessed. Global RV strain, global LV strain, and LV twist were decreased in patients with cToF. Global RV strain correlated with global LV strain (r = 0.66, p <0.001) and LV twist (r = -0.72, p <0.001), indicating the presence of adverse ventricular-ventricular interaction. Furthermore, close relations were observed between apical RV strain and apical LV strain (r = 0.62, p <0.001) and apical LV rotation (r = -0.67, p <0.001). In conclusion, RV strain was significantly related to LV strain and LV twist in patients with cToF and controls. Furthermore, apical RV strain correlated with apical LV strain and apical LV rotation, indicating adverse apical ventricular-ventricular interactions. |
| | |
Authors:
|
Annelies E van der Hulst; Victoria Delgado; Eduard R Holman; Lucia J M Kroft; Albert de Roos; Mark G Hazekamp; Nico A Blom; Jeroen J Bax; Arno A W Roest |
Related Documents
:
|
17495253 - Pathophysiological basis of right ventricular remodeling. 15234423 - Serial left ventricular adaptations in world-class professional cyclists: implications ... 2731523 - Effects of halothane, isoflurane and enflurane on isolated rat heart muscle. |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2010-07-23 |
Journal Detail:
|
Title: The American journal of cardiology Volume: 106 ISSN: 1879-1913 ISO Abbreviation: Am. J. Cardiol. Publication Date: 2010 Sep |
Date Detail:
|
Created Date: 2010-08-20 Completed Date: 2010-09-28 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0207277 Medline TA: Am J Cardiol Country: United States |
Other Details:
|
Languages: eng Pagination: 723-9 Citation Subset: AIM; IM |
Copyright Information:
|
2010 Elsevier Inc. All rights reserved. |
Affiliation:
|
Department of Pediatric Cardiology, Leiden, The Netherlands. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adolescent Case-Control Studies Child Cohort Studies Echocardiography, Doppler, Color Female Humans Magnetic Resonance Imaging Male Stress, Mechanical Stroke Volume Tetralogy of Fallot / complications*, physiopathology*, surgery Ventricular Dysfunction, Left / diagnosis, epidemiology*, physiopathology Ventricular Dysfunction, Right / diagnosis, epidemiology*, physiopathology Ventricular Remodeling / physiology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Atrial Arrhythmias in Patients With Arrhythmogenic Right Ventricular Cardiomyopathy/Dysplasia and Ve...
Next Document: Rate of Inducible Ventricular Arrhythmia in Adults With Congenital Heart Disease.