| Relation of Hand Enthesophytes with Knee Enthesopathy: Is Osteoarthritis Related to a Systemic Enthesopathy? | |
| | |
MedLine Citation:
|
PMID: 22174209 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
OBJECTIVE: Enthesopathy has been reported as a feature of osteoarthritis (OA) in the distal interphalangeal (DIP) joints. We previously reported that central bone marrow lesions (BML) on magnetic resonance imaging (MRI) scans are associated with OA. In this study, we evaluated whether hand and knee enthesopathy were related. METHODS: We studied knee and hand radiographs of subjects from the Framingham Osteoarthritis Study. Subjects seen in 2002-2005 had bilateral posteroanterior hand radiographs, weight-bearing knee radiographs, and knee MRI scans. Hand radiographs were read for enthesophytes at the juxtaarticular nonsynovial areas of metacarpophalangeal (MCP), proximal interphalangeal (PIP), and DIP joints, and midshafts of the phalanges. We selected 100 cases of knees with central BML and 100 matched controls. Conditional logistic regression was used to assess associations. RESULTS: Subjects with enthesophytes of at least 1 score ≥ 2 at DIP, PIP, and/or MCP were not more likely to have central knee BML (OR 0.49, 95% CI 0.17-1.40) than those without enthesophytes. Similarly, having at least 1 score ≥ 2 on the shafts was not significantly associated with having a central knee BML (OR 0.59, 95% CI 0.23-1.51). Adjustment for the presence of diabetes mellitus did not affect these results, but there was an increased prevalence of diabetes in those with hand enthesophytes (OR 3.09, 95% 1.29-7.40, enthesophyte score ≥ 2). CONCLUSION: We found no increase in the prevalence of hand enthesophytes among persons with central knee BML on their knee MRI scans. This provides evidence against a systemic enthesopathic disorder in association with knee OA. |
| | |
Authors:
|
Nadia Gibson; Ali Guermazi; Margaret Clancy; Jingbo Niu; Peter Grayson; Piran Aliabadi; Frank Roemer; David T Felson |
Related Documents
:
|
8010269 - Pituitary gland mr: a comparative study of healthy volunteers and patients with microad... 21542689 - Superparamagnetic nanosystems based on iron oxide nanoparticles for biomedical imaging. 20231369 - Mib-1 labeling index correlated with magnetic resonance imaging detected tumor volume d... 21287679 - Surface functionalization of superparamagnetic nanoparticles for the development of hig... 2013189 - A comparison of ct and mri in the assessment of the pituitary and parasellar region. 9002759 - [111in-dtpa-d-phe]-octreotide scintigraphy in functioning and non-functioning pituitary... 14643099 - The amygdala and schizophrenia: a volumetric magnetic resonance imaging study in first-... 21543179 - Acute chest pain: the role of mr imaging and mr angiography. 11867499 - Osteomyelitis pubis versus osteitis pubis: a case presentation and review of the litera... |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-12-15 |
Journal Detail:
|
Title: The Journal of rheumatology Volume: - ISSN: 0315-162X ISO Abbreviation: - Publication Date: 2011 Dec |
Date Detail:
|
Created Date: 2011-12-16 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 7501984 Medline TA: J Rheumatol Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
|
From the Departments of Clinical Epidemiology, Rheumatology and Radiology, Boston University Medical Center, and the Department of Radiology, Brigham and Women's Hospital, Boston, Massachusetts, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Platelet Reactivity and Disease Activity in Subjects with Psoriatic Arthritis.
Next Document: Clinical Characteristics of Patients with Remitting Seronegative Symmetrical Synovitis with Pitting ...