| Relation of femoral diameter, shear rate, and dilatory response to knee extensor exercise. | |
| | |
MedLine Citation:
|
PMID: 20308925 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
INTRODUCTION: Younger women typically exhibit marked dilation of the common femoral artery (CFA) during knee extensor exercise; this is in apparent contrast to subject groups with larger (men) and/or older (older women) vessels, which on average display much smaller exercise-induced increases in CFA diameter. To gain additional insight into this variation, the present study closely examined within- and between-group relationships among CFA diameter, shear rate, and the magnitude of exercise-induced CFA dilation. METHODS: Healthy women (15 younger and 18 older) and men (15 younger and 13 older) performed graded single-leg knee extensor exercise while CFA diameter and blood velocity were measured using Doppler ultrasound. RESULTS: Resting CFA diameter was smaller (P < 0.05) in women (younger: 0.71 ± 0.02 cm; older: 0.72 ± 0.02 cm) compared with men (younger: 0.84 ± 0.01 cm; older: 0.97 ± 0.03 cm). Resting CFA diameter was inversely associated with peak shear rate (combined groups: r = -0.83, P < 0.001) and the magnitude of dilation in women (younger: r = -0.82; older: r = -0.73, P < 0.001) and younger men (r = -0.66, P < 0.01) but not in older men (r = -0.17, P = 0.56). The dilatory response of the CFA to graded increases in shear rate showed a continuum across groups best described by a quadratic function (r2 = 0.89). Using piecewise regression modeling, a threshold diameter of 0.79 cm was identified below which diameter is inversely related to the magnitude of CFA dilation but above which little to no dilation was present. CONCLUSIONS: The CFA dilates to knee extensor exercise in women and men, the magnitude of which varies because of differences in shear rate across CFA diameters. |
| | |
Authors:
|
Joaquin U Gonzales; Julie A Miedlar; Beth A Parker; David N Proctor |
Related Documents
:
|
21983045 - Psycho-markers of weight loss. the roles of tfeq disinhibition and restraint in exercis... 15699535 - Training-related adaptations in motor unit discharge rate in young and older adults. 10995075 - Balance and strength of elderly chinese men and women. 15995265 - Exercise intervention designed to improve strength and dynamic balance among community-... 6431795 - Nitrate cross-tolerance: effect of sublingual isosorbide dinitrate and nitroglycerin du... 21116175 - Strength training following hematopoietic stem cell transplantation. |
Publication Detail:
|
Type: Journal Article; Research Support, N.I.H., Extramural |
Journal Detail:
|
Title: Medicine and science in sports and exercise Volume: 42 ISSN: 1530-0315 ISO Abbreviation: Med Sci Sports Exerc Publication Date: 2010 Oct |
Date Detail:
|
Created Date: 2010-09-21 Completed Date: 2011-01-13 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8005433 Medline TA: Med Sci Sports Exerc Country: United States |
Other Details:
|
Languages: eng Pagination: 1870-5 Citation Subset: IM; S |
Affiliation:
|
Department of Kinesiology, The Pennsylvania State University, University Park, PA 16802, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Age Factors Aged Blood Flow Velocity / physiology Exercise / physiology* Female Femoral Artery / physiology*, ultrasonography Humans Knee / blood supply*, physiology*, ultrasonography Male Sex Factors Shear Strength / physiology* Vasodilation / physiology* Young Adult |
| Grant Support | |
ID/Acronym/Agency:
|
M01 RR-10732/RR/NCRR NIH HHS; R01 AG018246/AG/NIA NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Reduced bone mass accrual in swim-trained prepubertal mice.
Next Document: Mechanisms for increases in V?O2max with endurance training in older and young women.