Document Detail


Related actions of probiotics and antibiotics on gut microbiota and weight modification.
MedLine Citation:
PMID:  24070562     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Antibiotics and probiotics are widely used as growth promoters in agriculture. Most antibiotics prescribed in clinical practice are natural products that originate from Streptomyces spp, which were first used as agricultural probiotics. Antibiotics and probiotics both modify the gut microbiota. The effect of a probiotic species on the digestive flora depends on the strain and is largely determined by bacteriocin production. In human beings, as in animals, specific probiotics are associated with weight gain or loss. Improved understanding of the ability of specific probiotics to harvest energy from the host diet might lead to development of new treatments for obesity and malnutrition. In this Review, we present the effects of probiotics and antibiotics on the gut microbiota of human beings and animals and discuss their potential therapeutic use as interventions for weight gain and loss in human beings.
Authors:
Emmanouil Angelakis; Vicky Merhej; Didier Raoult
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  The Lancet. Infectious diseases     Volume:  13     ISSN:  1474-4457     ISO Abbreviation:  Lancet Infect Dis     Publication Date:  2013 Oct 
Date Detail:
Created Date:  2013-09-27     Completed Date:  2013-11-14     Revised Date:  2014-08-15    
Medline Journal Info:
Nlm Unique ID:  101130150     Medline TA:  Lancet Infect Dis     Country:  United States    
Other Details:
Languages:  eng     Pagination:  889-99     Citation Subset:  IM    
Copyright Information:
Copyright © 2013 Elsevier Ltd. All rights reserved.
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MeSH Terms
Descriptor/Qualifier:
Animals
Anti-Bacterial Agents / pharmacology*
Bacteria / drug effects*
Body Weight / drug effects*
Humans
Intestines / microbiology*
Probiotics / pharmacology*
Chemical
Reg. No./Substance:
0/Anti-Bacterial Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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