| Relapsing vivax malaria despite chemoprophylaxis in two blood donors who had travelled to Papua New Guinea. | |
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MedLine Citation:
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PMID: 20402614 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Two Australian blood donors were diagnosed with relapsing Plasmodium vivax malaria 5 and 15 months, respectively, after their most recent travel to a malaria-endemic country. Common features included travel to Papua New Guinea (specifically, the Kokoda Trail); full compliance with recommended malaria chemoprophylaxis; and negative results on malaria antibody testing at the time of donation. Although all fresh blood components from the two donors issued on the basis of these negative results were recalled before transfusion, these cases underscore the increased potential for relapse of P. vivax in donors returning from malaria-endemic countries, as well as the inability to identify the potential for relapse using current malarial screening tests. |
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Authors:
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Clive R Seed; Jacqueline T Coughlin; Anne M Pickworth; Robert J Harley; Anthony J Keller |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: The Medical journal of Australia Volume: 192 ISSN: 0025-729X ISO Abbreviation: Med. J. Aust. Publication Date: 2010 Apr |
Date Detail:
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Created Date: 2010-04-20 Completed Date: 2010-06-07 Revised Date: 2010-11-01 |
Medline Journal Info:
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Nlm Unique ID: 0400714 Medline TA: Med J Aust Country: Australia |
Other Details:
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Languages: eng Pagination: 471-3 Citation Subset: IM |
Affiliation:
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Australian Red Cross Blood Service, Perth, WA, Australia. cseed@arcbs.redcross.org.au |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Antibodies, Protozoan / blood* Antimalarials / therapeutic use* Australia Blood Donors* Blood Transfusion Chemoprevention Enzyme-Linked Immunosorbent Assay / methods Humans Malaria, Vivax / diagnosis*, enzymology, immunology, prevention & control* Male Middle Aged Papua New Guinea Plasmodium vivax / isolation & purification* Travel* |
| Chemical | |
Reg. No./Substance:
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0/Antibodies, Protozoan; 0/Antimalarials |
| Comments/Corrections | |
Comment In:
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Med J Aust. 2010 Oct 18;193(8):484
[PMID:
20955130
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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