Document Detail


Relapsing polychondritis and malignant lymphoma: is polychondritis paraneoplastic?
MedLine Citation:
PMID:  17224547     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Relapsing polychondritis (RP) is associated with other rheumatic or autoimmune disease in about 30% of cases; however, an association with malignancy is rare with the exception of myelodysplastic syndrome (MDS). Observation Herein we report the first case, to our knowledge, of RP following splenic non-Hodgkin lymphoma (NHL), and we have reviewed all the previous well-documented reports that described the cases of RP associated with malignant lymphoma (ML).
CONCLUSIONS: Our case and the review of reported cases showed that RP preceded ML in 2 cases, RP occurred after diagnosis and treatment of ML in 2 cases, and RP and ML occurred simultaneously in 1 case. The types of ML encountered were Hodgkin lymphoma, orbital mucosa associated lymphoid tissue type lymphoma, nodal NHL, and splenic NHL. From the frequent association of RP with MDS and, less frequently, with ML, we speculate that some RP cases may occur as a paraneoplastic condition of the concurrent hematological malignancies.
Authors:
Teruki Yanagi; Tetsuri Matsumura; Ryuta Kamekura; Noriko Sasaki; Satoshi Hashino
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Archives of dermatology     Volume:  143     ISSN:  0003-987X     ISO Abbreviation:  Arch Dermatol     Publication Date:  2007 Jan 
Date Detail:
Created Date:  2007-01-16     Completed Date:  2007-02-14     Revised Date:  2013-05-20    
Medline Journal Info:
Nlm Unique ID:  0372433     Medline TA:  Arch Dermatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  89-90     Citation Subset:  AIM; IM    
Affiliation:
Departments of Dermatology, Otolaryngology, and Ophthalmology, Tonan Hospital, Sapporo, Japan. yanagi@med.hokudai.ac.jp
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MeSH Terms
Descriptor/Qualifier:
Diagnosis, Differential
Female
Humans
Lymphoma / complications*,  diagnosis
Middle Aged
Paraneoplastic Syndromes / diagnosis,  etiology*
Polychondritis, Relapsing / diagnosis,  etiology*
Comments/Corrections
Comment In:
Arch Dermatol. 2007 Jul;143(7):949-50   [PMID:  17638749 ]

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