| Relapse of enterococcal prosthetic valve endocarditis with aortic root abscess following treatment with daptomycin in a patient not fit for surgery. | |
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MedLine Citation:
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PMID: 20019148 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Daptomycin is a novel lipopeptide with activity against Gram-positive organisms including enterococci. It is licensed for the treatment of Staphylococcus aureus bacteraemia and right-sided endocarditis, but not endocarditis due to Enterococcus spp. We report a case of enterococcal prosthetic valve endocarditis with an aortic root abscess in an elderly patient who was not fit for surgery. The patient's endocarditis relapsed 9 weeks after a 6 week course of daptomycin. |
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Authors:
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D A Enoch; N Phillimore; J A Karas; L Horswill; D A Mlangeni |
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Publication Detail:
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Type: Case Reports; Journal Article Date: 2009-12-17 |
Journal Detail:
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Title: Journal of medical microbiology Volume: 59 ISSN: 1473-5644 ISO Abbreviation: J. Med. Microbiol. Publication Date: 2010 Apr |
Date Detail:
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Created Date: 2010-03-17 Completed Date: 2010-04-07 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0224131 Medline TA: J Med Microbiol Country: England |
Other Details:
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Languages: eng Pagination: 482-5 Citation Subset: IM |
Affiliation:
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Clinical Microbiology and Public Health Laboratory, Peterborough District Hospital, Thorpe Road, Peterborough PE3 6JW, UK. david.enoch@pbh-tr.nhs.uk |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Abscess
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drug therapy,
etiology* Aged Aged, 80 and over Amoxicillin / therapeutic use Anti-Bacterial Agents / therapeutic use* Aortic Valve / microbiology, surgery* Bacteremia / drug therapy, etiology* Daptomycin / therapeutic use* Endocarditis, Bacterial / drug therapy, etiology* Enterococcus faecalis / drug effects, isolation & purification* Female Heart Valve Prosthesis / adverse effects* Humans Recurrence |
| Chemical | |
Reg. No./Substance:
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0/Anti-Bacterial Agents; 103060-53-3/Daptomycin; 26787-78-0/Amoxicillin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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