Document Detail

Reiter's syndrome during intravesical BCG therapy for bladder carcinoma.
MedLine Citation:
PMID:  16912847     Owner:  NLM     Status:  MEDLINE    
A 50-year-old male with superficial bladder carcinoma developed fever, conjunctivitis, cystitis, and arthritis of the ankles and metatarsophalangeal and sacroiliac joints after the fourth course of intravesical Bacillus Calmette-Guerin (BCG) therapy. Reiter's syndrome in the context of BCG therapy was diagnosed, and intravesical immunotherapy was discontinued. Treatment with indomethacin was started with partial response, while a significant clinical improvement was noted when prednisolone 30 mg daily was started. One month later, the patient was on full clinical and laboratory remission, and steroid treatment was gradually tapered. Clinicians should be aware of this rare complication of BCG therapy because early diagnosis may lead to early management.
Maria G Tektonidou
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2006-08-16
Journal Detail:
Title:  Clinical rheumatology     Volume:  26     ISSN:  0770-3198     ISO Abbreviation:  Clin. Rheumatol.     Publication Date:  2007 Aug 
Date Detail:
Created Date:  2007-06-28     Completed Date:  2007-09-04     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8211469     Medline TA:  Clin Rheumatol     Country:  Belgium    
Other Details:
Languages:  eng     Pagination:  1368-9     Citation Subset:  IM    
Department of Internal Medicine, Euroclinic Hospital, 9 Athanasiadou str, 11521, Athens, Greece.
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MeSH Terms
Antineoplastic Agents / adverse effects*
Arthritis, Reactive / chemically induced*,  drug therapy
BCG Vaccine / adverse effects*
Carcinoma / drug therapy
Middle Aged
Urinary Bladder Neoplasms / drug therapy
Reg. No./Substance:
0/Antineoplastic Agents; 0/BCG Vaccine

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