Document Detail

Reirradiation of recurrent glioblastoma.
MedLine Citation:
PMID:  21312096     Owner:  NLM     Status:  Publisher    
Patients with glioblastoma are treated by radiotherapy in combination with temozolamid. Recurrent and progressive disease can be managed by several treatment options. Some series reported about reirradiation of brain tumors, but there are no randomised studies. Modern high precise radiation techniques can be an option for a save and effective treatment without systemic side effects. The published series show median survival rates from 6 to 12 months. Concomitant systemic therapies are evaluated in phase I/II studies. Indication for irradiation and decision of the technique and fractionation scheme have to be chosen individually. There is no curative intent for reirradiation, possible serious side effects and negative influence on life quality have to be omitted.
Dietmar Seewald
Publication Detail:
Journal Detail:
Title:  Wiener medizinische Wochenschrift (1946)     Volume:  161     ISSN:  1563-258X     ISO Abbreviation:  -     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2011-2-11     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8708475     Medline TA:  Wien Med Wochenschr     Country:  -    
Other Details:
Languages:  GER     Pagination:  22-25     Citation Subset:  -    
Abteilung für Radio-Onkologie - Strahlentherapie, Landeskrankenhaus Vöcklabruck, Vöcklabruck, Austria,
Vernacular Title:
Neuerliche Radiotherapie beim Rezidiv des Glioblastoma multiforme.
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