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Reinvestigation of the Alkaloid Composition of Atropa belladonna Plants, Root Cultures, and Cell Suspension Cultures.
MedLine Citation:
PMID:  17345349     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
The alkaloid composition of ATROPA BELLADONNA was analyzed by high resolution GLC and GLC-MS. A total of 13 alkaloids, most new for ATROPA, were identified from roots. The aboveground parts of the plant revealed 7 alkaloids; the hygrines were completely absent. The alkaloid pattern of root cultures was almost identical with the pattern of roots from intact plants. The patterns differed only quantitatively. Scopolamine which in A. BELLADONNA seems to be synthesized in the roots only, was preferably excreted into the culture medium. Norhyoscyamine was found frequently in plant shoots. The occurrence of hyoscyamine N-oxide in various plant organs could be confirmed. Cell suspension cultures produced trace amounts of hyoscyamine, 3alpha-acetoxytropane and 3alpha-tigloyloxytropane. The last two ester alkaloids were not detectable in intact plants.
Authors:
T Hartmann; L Witte; F Oprach; G Toppel
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Planta medica     Volume:  -     ISSN:  0032-0943     ISO Abbreviation:  Planta Med.     Publication Date:  1986 Oct 
Date Detail:
Created Date:  2007-03-08     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0066751     Medline TA:  Planta Med     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  390-5     Citation Subset:  -    
Affiliation:
Institut für Pharmazeutische Biologie der Technischen Universität, Mendelssohnstr. 1, D-3300 Braunschweig, Federal Republic of Germany.
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