Document Detail

Reinfection with Legionella pneumophila documented by pulsed-field gel electrophoresis.
MedLine Citation:
PMID:  7888549     Owner:  NLM     Status:  MEDLINE    
A 50-year-old man with chronic lymphocytic leukemia experienced two episodes of community-acquired legionnaires' disease. For determining whether this was the result of relapse or reinfection, Legionella pneumophila strains, cultured from sputum specimens and his home water supply, were characterized by pulsed-field gel electrophoresis. Analysis of the restriction patterns and the clinical data indicated that the second disease period was most likely the result of reinfection. We conclude that after diagnosis of community-acquired legionnaires' disease in an immunocompromised patient, culturing of the domestic water supplies for L. pneumophila should be considered; if such cultures are positive, adequate measures to prevent reexposure have to be taken.
M A Leverstein-van Hall; A Verbon; M V Huisman; E J Kuijper; J Dankert
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America     Volume:  19     ISSN:  1058-4838     ISO Abbreviation:  Clin. Infect. Dis.     Publication Date:  1994 Dec 
Date Detail:
Created Date:  1995-04-17     Completed Date:  1995-04-17     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9203213     Medline TA:  Clin Infect Dis     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1147-9     Citation Subset:  IM    
Department of Medical Microbiology, University of Amsterdam, the Netherlands.
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MeSH Terms
Anti-Bacterial Agents
Community-Acquired Infections / diagnosis,  microbiology
DNA, Bacterial / analysis
Drug Therapy, Combination / therapeutic use
Electrophoresis, Gel, Pulsed-Field
Immunocompromised Host
Legionella pneumophila / genetics,  isolation & purification*
Legionnaires' Disease / diagnosis*,  drug therapy,  microbiology
Leukemia, Lymphoid / complications
Middle Aged
Sputum / microbiology
Water Microbiology*
Reg. No./Substance:
0/Anti-Bacterial Agents; 0/DNA, Bacterial

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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