| Reibergram of intrathecal synthesis of C4 in patients with eosinophilic meningitis caused by Angiostrongylus cantonensis. | |
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MedLine Citation:
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PMID: 20519605 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Angiostrongylus cantonensis produces eosinophilic meningitis in humans and is endemic in Thailand, Taiwan, China, and the Caribbean region. During infection with this parasite, it is important to know if the complement system may be activated by the classical or lectin pathway. Cerebrospinal fluid and serum samples from 20 patients with meningitic angiostrongyliasis were used to quantify C4 levels and albumin. Results were plotted on a C4 CSF/serum quotient diagram or Reibergram. Twelve patients showed intrathecal synthesis of C4. Antibody-dependent complement cytotoxicity should be considered as a possible mechanism that destroys third-stage larvae of this helminth in cerebrospinal fluid of affected patients. |
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Authors:
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Bárbara Padilla-Docal; Alberto Juan Dorta-Contreras; Raisa Bu-Coifiu-Fanego; Alexis Rodríguez-Rey; Juan Carlos Gutiérrez-Hernández; Susana Olga de Paula-Almeida |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The American journal of tropical medicine and hygiene Volume: 82 ISSN: 1476-1645 ISO Abbreviation: Am. J. Trop. Med. Hyg. Publication Date: 2010 Jun |
Date Detail:
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Created Date: 2010-06-03 Completed Date: 2010-06-23 Revised Date: 2011-07-28 |
Medline Journal Info:
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Nlm Unique ID: 0370507 Medline TA: Am J Trop Med Hyg Country: United States |
Other Details:
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Languages: eng Pagination: 1094-8 Citation Subset: AIM; IM |
Affiliation:
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Central Laboratory of Cerebrospinal Fluid, Faculty of Medical Sciences Dr. Miguel Enriquez, Havana Medical Sciences University, Havana, Cuba. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Angiostrongylus cantonensis* Animals Antibodies, Helminth Child Child, Preschool Complement C4 / cerebrospinal fluid*, metabolism Eosinophilia / blood, cerebrospinal fluid, parasitology* Female Humans Infant Male Meningitis / blood, cerebrospinal fluid*, parasitology* Strongylida Infections / blood, cerebrospinal fluid* Young Adult |
| Chemical | |
Reg. No./Substance:
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0/Antibodies, Helminth; 0/Complement C4 |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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