| Rehabilitation of patients with congestive heart failure with or without beta-blockade therapy. | |
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MedLine Citation:
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PMID: 11561225 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Management of heart failure includes beta-blockade (betaB) therapy and cardiac rehabilitation. The aim of this study was to compare the exercise training response of patients with congestive heart failure (CHF) receiving betaB therapy with that of patients not receiving treatment. METHODS AND RESULTS: Thirty-four consecutive patients with CHF were included in a 4-week training program at their ventilatory threshold (VT); 6 patients received betaB treatment and 18 did not. The patients underwent a cardiopulmonary exercise test before and after training. Oxygen uptake (VO(2)) at peak exercise and at VT increased in both groups (P < or =.0001) without any significant differences between the groups. The same results were found after adjustment to ejection fraction and VO(2) at the start of the training program. There was no difference in VT improvement, measured as a percentage of utilization of maximal oxygen uptake, between the groups. After training, heart rate and ventilation decreased (P < or =.0001) at submaximal levels in both groups without significant differences between the groups. CONCLUSIONS: betaB therapy does not impair functional improvement induced by a rehabilitation program in patients with CHF. betaB therapy does not interfere with exercise training prescription if patient exercise evaluations are made at the time of therapeutic intake. |
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Authors:
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D Curnier; M Galinier; A Pathak; J Fourcade; M Bousquet; J M Senard; J M Fauvel; J P Bounhoure; J L Montastruc |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Journal of cardiac failure Volume: 7 ISSN: 1071-9164 ISO Abbreviation: J. Card. Fail. Publication Date: 2001 Sep |
Date Detail:
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Created Date: 2001-09-18 Completed Date: 2001-10-11 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9442138 Medline TA: J Card Fail Country: United States |
Other Details:
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Languages: eng Pagination: 241-8 Citation Subset: IM |
Affiliation:
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INSERM Unité 317, Laboratoire de Pharmacologie Clinique et Expérimentale, Faculté de Médecine, Toulouse, France. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adrenergic beta-Antagonists
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therapeutic use* Case-Control Studies Exercise Test Exercise Therapy* Heart Failure / drug therapy*, rehabilitation* Heart Rate Humans Middle Aged Oxygen Consumption Prospective Studies Pulmonary Ventilation Time Factors |
| Chemical | |
Reg. No./Substance:
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0/Adrenergic beta-Antagonists |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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