Document Detail


Rehabilitation of neuromyelitis optica (Devic syndrome): three case reports.
MedLine Citation:
PMID:  17993984     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We describe the inpatient clinical rehabilitation course of three patients with neuromyelitis optica (NMO; Devic syndrome). These patients had varying functional deficits. Each patient improved in several functional independence measures (FIM domains) but had minimal to no progress in other domains after acute rehabilitation stays between 1 and 1.5 mos. NMO is a severe central nervous system demyelinating syndrome distinct from MS, characterized by optic neuritis, myelitis, and at least two of three criteria: longitudinally extensive cord lesion, MRI nondiagnostic for multiple sclerosis, or NMO-IgG seropositivity. Persons with NMO may demonstrate improved function with rehabilitation efforts; though gains may be lost to relapse. Future immunomodulatory intervention may augment the benefits of rehabilitation.
Authors:
Adam L Schreiber; Guy W Fried; Christopher S Formal; Bryan X DeSouza
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  American journal of physical medicine & rehabilitation / Association of Academic Physiatrists     Volume:  87     ISSN:  0894-9115     ISO Abbreviation:  Am J Phys Med Rehabil     Publication Date:  2008 Feb 
Date Detail:
Created Date:  2008-01-22     Completed Date:  2008-03-19     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8803677     Medline TA:  Am J Phys Med Rehabil     Country:  United States    
Other Details:
Languages:  eng     Pagination:  144-8     Citation Subset:  AIM; IM    
Affiliation:
Department of Rehabilitation, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA.
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MeSH Terms
Descriptor/Qualifier:
Adult
Diagnosis, Differential
Female
Health Status Indicators
Humans
Middle Aged
Multiple Sclerosis / diagnosis
Neuromyelitis Optica / diagnosis,  rehabilitation*
Treatment Outcome*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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