Document Detail

Rehabilitation and multiple sclerosis: hot topics in the preservation of physical functioning.
MedLine Citation:
PMID:  22206766     Owner:  NLM     Status:  Publisher    
In a chronic and disabling disease like multiple sclerosis, rehabilitation becomes of major importance in the preservation of physical, psychological and social functioning. Approximately 80% of patients have multiple sclerosis for more than 35 years and most will develop disability at some point of their lives, emphasising the importance of rehabilitation in order to maintain quality of life. An important aspect of multiple sclerosis rehabilitation is the preservation of physical functioning. Hot topics in the rehabilitation of physical function include (1) exercise therapy, (2) robot-assisted training and (3) pharmacological interventions. Exercise therapy has for many years been a controversial issue in multiple sclerosis rehabilitation and the advice generally given to patients was not to participate in physical exercise, since it was thought to lead to a worsening of symptoms or fatigue. However, a paradigm shift is taking place and it is now increasingly acknowledged that exercise therapy is both safe and beneficial. Robot-assisted training is also attracting attention in multiple sclerosis rehabilitation. Several sophisticated commercial robots exist, but so far the number of scientific studies that have evaluated these is limited, although some promising results have been reported. Finally, recent studies have shown that certain pharmacological interventions have the potential to improve functional capacity substantially, with the potassium channel blocker fampridine being one of the most promising. This drug has been shown to improve walking ability in some patients with multiple sclerosis, associated with a reduction of patients' self-reported ambulatory disability. Rehabilitation strategies involving these different approaches, or combinations of them, may be of great use in improving everyday functioning and quality of life in patients with MS.
Ulrik Dalgas
Related Documents :
8857226 - Perception and use of insect repellent among soldiers in the singapore armed forces.
16836696 - Lung function after acute and repeated exposures to extremely cold air (-110 degrees c)...
11322466 - Testing the validity of erythema detection algorithms.
8337276 - A skin-stretching device for the harnessing of the viscoelastic properties of skin.
22285356 - Finite element modeling of tmj joint disc behavior.
2137986 - Enhanced calcium uptake of cardiac sarcoplasmic reticulum in exercise-trained old rats.
Publication Detail:
Journal Detail:
Title:  Journal of the neurological sciences     Volume:  311S1     ISSN:  1878-5883     ISO Abbreviation:  -     Publication Date:  2011 Dec 
Date Detail:
Created Date:  2011-12-30     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0375403     Medline TA:  J Neurol Sci     Country:  -    
Other Details:
Languages:  ENG     Pagination:  S43-S47     Citation Subset:  -    
Copyright Information:
Copyright © 2011 Elsevier B.V. All rights reserved.
Department of Sport Science, University of Aarhus, Aarhus, Denmark.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Review of methodological issues of clinical trials in multiple sclerosis.
Next Document:  Symptom management in patients with multiple sclerosis.