Document Detail


Regulatory peptides in endocrine cells and autonomic nerves: electron immunocytochemistry.
MedLine Citation:
PMID:  6947395     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Advances in immunocytochemistry, particularly at the electron microscope level, have enabled us to establish further details of the ultrastructural appearance of endocrine cells and autonomic nerves of the gastrointestinal tract. Its contribution can be summarised as follows: a)validation of previously recognised endocrine cell types. b) Recognition of sub-groups within endocrine cells and autonomic nerve cell types previously included within one single type (e.g. D1 cells and p-type autonomic nerves). c) Discrimination of molecular forms now known to be stored in morphologically distinguishable secretory granules or parts thereof (e.g. pro-glucagon and glucagon in A cells and gut and antral gastrin-producing cells). Advances in the techniques and the accurate quantification of the end products will enable us to recognise changes in gastrointestinal tract diseases in man.
Authors:
J M Polak; A M Buchan; L Probert; F Tapia; J de Mey; S R Bloom
Related Documents :
885785 - The structure of the cells lining the stomach of the tammar wallaby (macropus eugenii).
17012845 - Histamine-mediated signaling processes in human malignant mammary cells.
8973475 - Single-cell mutation analysis of tumors from stained histologic slides.
478195 - Effect of somatostatin on normal and gastric-stimulated cell proliferation in the gastr...
21463255 - Role of progesterone in human astrocytomas growth.
411525 - Affinity of bronchial secretion glycoproteins and cells of human bronchial mucosa for r...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Scandinavian journal of gastroenterology. Supplement     Volume:  70     ISSN:  0085-5928     ISO Abbreviation:  Scand. J. Gastroenterol. Suppl.     Publication Date:  1981  
Date Detail:
Created Date:  1982-02-22     Completed Date:  1982-02-22     Revised Date:  2008-02-13    
Medline Journal Info:
Nlm Unique ID:  0437034     Medline TA:  Scand J Gastroenterol Suppl     Country:  NORWAY    
Other Details:
Languages:  eng     Pagination:  11-23     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Animals
Autonomic Nervous System / analysis,  anatomy & histology*
Cytoplasmic Granules / analysis
Digestive System / innervation*
Gastrins / analysis
Gastrointestinal Hormones / analysis*
Glucagon / analysis
Humans
Immunochemistry
Microscopy, Electron
Proglucagon
Protein Precursors / analysis
Chemical
Reg. No./Substance:
0/Gastrins; 0/Gastrointestinal Hormones; 0/Protein Precursors; 55963-74-1/Proglucagon; 9007-92-5/Glucagon

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  The ultrastructure of some gastrointestinal lesions in experimental animals and man.
Next Document:  The quantification of zinc in the mucosal cells of human small intestine using x-ray microanalysis.