Document Detail


Regulatory long non-coding RNA and its functions.
MedLine Citation:
PMID:  22535282     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
The discovery of large numbers of long non-coding RNAs (lncRNAs) has been driven by genome-wide transcriptional analyses. Compared to small ncRNAs, lncRNAs have been shown to harbor biological activities, but the functions of the great majority of lncRNAs are not known. There is growing evidence that lncRNAs can regulate gene expression at epigenetic, transcription, and post-transcription levels and widely take part in various physiological and pathological processes, such as participating in cell development, immunity, oncogenesis, clinical disease processes, etc. Here, the current research efforts on the function of lncRNA in recent years were summarized.
Authors:
Yong Huang; Ning Liu; Jian Ping Wang; Yu Qin Wang; Xue Li Yu; Zhan Bin Wang; Xiang Chao Cheng; Quan Zou
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-4-26
Journal Detail:
Title:  Journal of physiology and biochemistry     Volume:  -     ISSN:  1877-8755     ISO Abbreviation:  -     Publication Date:  2012 Apr 
Date Detail:
Created Date:  2012-4-26     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9812509     Medline TA:  J Physiol Biochem     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Animal Science and Technology College, He Nan University of Science and Technology, Luoyang City, 471003, Henan Province, People's Republic of China.
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