| Regulatory characteristics of the Vibrio vulnificus rtxHCA operon encoding a MARTX toxin. | |
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MedLine Citation:
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PMID: 22996810 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Vibrio vulnificus MARTX encoded by rtxA, an open reading frame of the rtxHCA operon, is essential for virulence in vitro and in mice. In this study, a primer extension analysis revealed that transcription of the rtxHCA operon begins at a single site, and is under the direction of a single promoter, P( rtxHCA ). P( rtxHCA ) activity appeared at the beginning of growth and reached a maximum in mid-exponential phase. P( rtxHCA ) activity was induced by exposure to INT-407 cells, and the membrane fraction of INT-407 cells was the most effective for the induction. |
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Authors:
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Jinseo Park; Seung Min Kim; Hee Gon Jeong; Sang Ho Choi |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-9-21 |
Journal Detail:
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Title: Journal of microbiology (Seoul, Korea) Volume: - ISSN: 1976-3794 ISO Abbreviation: J. Microbiol. Publication Date: 2012 Sep |
Date Detail:
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Created Date: 2012-9-21 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9703165 Medline TA: J Microbiol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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National Research Laboratory of Molecular Microbiology and Toxicology, Department of Agricultural Biotechnology, Center for Food Safety and Toxicology, Seoul National University, Seoul, 151-921, Republic of Korea. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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