Document Detail


Regulatory T cells in central nervous system: in health and disease.
MedLine Citation:
PMID:  20868354     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Regulatory T cells participate in several immune responses including autoimmune reactions inducing self-tolerance, tumor immunity, transplantation tolerance and microbial infection. Nevertheless regulatory T cells actions seem to be different when they are in the central nervous system (CNS), since they interact with resident cells of the CNS, according to the particular conditions elicited in this compartment. This review focuses on the role of regulatory T cells in health, autoimmune and other CNS diseases, pointing out their interactions with resident CNS cells.
Authors:
Brenda Saenz; Jesús Pérez-H; Anahí Chavarría
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Central nervous system agents in medicinal chemistry     Volume:  10     ISSN:  1875-6166     ISO Abbreviation:  Cent Nerv Syst Agents Med Chem     Publication Date:  2010 Dec 
Date Detail:
Created Date:  2010-12-21     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101269163     Medline TA:  Cent Nerv Syst Agents Med Chem     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  326-36     Citation Subset:  IM    
Affiliation:
Departamento de Inmunología, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, México. anahi.chavarria@gmail.com.
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