| Regulation of substrate uptake in Nocardia erythropolis. | |
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MedLine Citation:
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PMID: 4828306 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The regulation of uptake of glucose (GLU), glycerol (GLY), mannitol (MTL), and succinate (SUC) has been examined in Nocardia erythropolis 305. The apparent K(m) values of the uptake activities of cells subcultured in a medium with the corresponding substrate as the sole carbon source were 205, 48, 8.7, and 36 muM for GLU, GLY, MTL, and SUC, respectively. GLU and GLY uptake activities were constitutive, although there was evidence for an additional inducible component in GLY uptake. Moreover, MTL and SUC uptake activities were inducible. MTL uptake activity was markedly induced by cultivation in MTL medium and partially induced by growth in GLU medium, whereas SUC uptake was induced only by cultivation in SUC medium. SUC added to MTL medium partially repressed the formation of, or inhibited the activity of, MTL uptake. When not induced, uptake of MTL and SUC was proportional to the substrate concentration. The induced uptake of MTL and SUC and the constitutive uptake of GLU were energy dependent and carrier mediated. Uptake of GLY, constitutively or when induced, was also carrier mediated. |
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Authors:
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R H Pang; S G Bradley |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of bacteriology Volume: 118 ISSN: 0021-9193 ISO Abbreviation: J. Bacteriol. Publication Date: 1974 May |
Date Detail:
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Created Date: 1974-07-16 Completed Date: 1974-07-16 Revised Date: 2010-09-13 |
Medline Journal Info:
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Nlm Unique ID: 2985120R Medline TA: J Bacteriol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 400-6 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Azides
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pharmacology Biological Transport, Active Carbon Radioisotopes Chloromercuribenzoates / pharmacology Culture Media Cyanides / pharmacology Diffusion Dinitrophenols / pharmacology Dithiothreitol / pharmacology Glucose / metabolism* Glycerol / metabolism* Mannitol / metabolism* Nocardia / metabolism* Succinates / metabolism* Temperature Time Factors |
| Chemical | |
Reg. No./Substance:
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0/Azides; 0/Carbon Radioisotopes; 0/Chloromercuribenzoates; 0/Culture Media; 0/Cyanides; 0/Dinitrophenols; 0/Succinates; 3483-12-3/Dithiothreitol; 50-99-7/Glucose; 56-81-5/Glycerol; 69-65-8/Mannitol |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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