Document Detail

Regulation of sterol biosynthesis in Saccharomyces cerevisiae.
MedLine Citation:
PMID:  7729765     Owner:  NLM     Status:  MEDLINE    
Sterol synthesis in Saccharomyces cerevisiae was primarily controlled by the growth rate. At low specific growth rates the intermediates of ergosterol biosynthesis prevailed in cells. At the same time, the total sterol content reached about 6% of dry matter whereas the content of ergosterol was only 2-2.5%, which seems to be the maximum value for S. cerevisiae. After esterification with fatty acids these sterol intermediates are stored in lipid globules together with reserve triacylglycerols. The sporulating S. cerevisiae cells contained 3.5% sterols and 1.5% ergosterol of dry matter.
B Bĕhalová; M Bláhová; V Bĕhal
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Folia microbiologica     Volume:  39     ISSN:  0015-5632     ISO Abbreviation:  Folia Microbiol. (Praha)     Publication Date:  1994  
Date Detail:
Created Date:  1995-05-30     Completed Date:  1995-05-30     Revised Date:  2000-12-18    
Medline Journal Info:
Nlm Unique ID:  0376757     Medline TA:  Folia Microbiol (Praha)     Country:  CZECH REPUBLIC    
Other Details:
Languages:  eng     Pagination:  287-90     Citation Subset:  IM    
Institute of Microbiology, Academy of Sciences of the Czech Republic, Prague.
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MeSH Terms
Culture Media
Ergosterol / biosynthesis
Fatty Acids / metabolism
Nitrogen / metabolism
Saccharomyces cerevisiae / growth & development,  metabolism*,  physiology
Spores, Fungal / metabolism
Sterols / biosynthesis*,  chemistry
Triglycerides / metabolism
Reg. No./Substance:
0/Culture Media; 0/Fatty Acids; 0/Sterols; 0/Triglycerides; 57-87-4/Ergosterol; 7727-37-9/Nitrogen

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