| Regulation of mitochondrial gene expression by retinoids. | |
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MedLine Citation:
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PMID: 12440518 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Several nuclear hormone receptors have been localized to the mitochondrial compartment. Evidence supports the hypothesis that these receptors directly regulate mitochondrial transcription. Retinoic acid has also been shown to regulate mitochondrial transcription and function. This review discusses mechanisms of mitochondrial transcription and how retinoic acid may either indirectly or directly regulate mitochondrial transcription. How retinoic acid may affect individual nutrient requirements is also discussed. |
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Authors:
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Helen B Everts; Carolyn D Berdanier |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Review |
Journal Detail:
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Title: IUBMB life Volume: 54 ISSN: 1521-6543 ISO Abbreviation: IUBMB Life Publication Date: 2002 Aug |
Date Detail:
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Created Date: 2002-11-20 Completed Date: 2003-07-01 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 100888706 Medline TA: IUBMB Life Country: England |
Other Details:
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Languages: eng Pagination: 45-9 Citation Subset: IM |
Affiliation:
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Department of Foods and Nutrition, University of Georgia, Athens 30602, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Binding Sites DNA, Mitochondrial / genetics, metabolism* Forecasting Gene Expression Regulation / drug effects* Humans Models, Genetic Promoter Regions, Genetic Receptors, Retinoic Acid / drug effects, genetics, metabolism* Receptors, Thyroid Hormone / metabolism Transcription, Genetic Tretinoin / metabolism, pharmacology* |
| Chemical | |
Reg. No./Substance:
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0/DNA, Mitochondrial; 0/Receptors, Retinoic Acid; 0/Receptors, Thyroid Hormone; 302-79-4/Tretinoin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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