Document Detail


Regulation of iron therapy by S-ferritin estimations in patients on chronic hemodialysis.
MedLine Citation:
PMID:  7244567     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Serum ferritin estimation was compared with bone marrow hemosiderin staining in the primary diagnosis of iron deficiency and overload in 19 patients on chronic hemodialysis. Serum ferritin estimation had a high predictive value: all 8 patients with marrow iron grade III had elevated S-ferritin values, and 3 out of 5 iron-deficient patients had subnormal values, the other 2 low-normal values. Serum iron and transferrin estimation was of very little value. Prophylactic treatment with 100 mg iron sulphate daily p.o. was inadequate for 13 of the 19 patients: 8 had iron overload. 5 had iron deficiency. Iron sulphate therapy was monitored by bone marrow hemosiderin and serum ferritin values and 15 patients could be followed up for one year. It was shown that serum ferritin estimations could be used to monitor the iron therapy.
Authors:
G Birgegård; P Nilsson; L Wide
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Scandinavian journal of urology and nephrology     Volume:  15     ISSN:  0036-5599     ISO Abbreviation:  Scand. J. Urol. Nephrol.     Publication Date:  1981  
Date Detail:
Created Date:  1981-08-10     Completed Date:  1981-08-10     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0114501     Medline TA:  Scand J Urol Nephrol     Country:  SWEDEN    
Other Details:
Languages:  eng     Pagination:  69-72     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Anemia, Hypochromic / diagnosis,  etiology*,  prevention & control
Bone Marrow Examination
Female
Ferritins / blood*
Hemosiderin / analysis*
Humans
Iron / therapeutic use*
Kidney Failure, Chronic / complications,  therapy
Male
Middle Aged
Renal Dialysis / adverse effects*
Chemical
Reg. No./Substance:
7439-89-6/Iron; 9007-73-2/Ferritins; 9011-92-1/Hemosiderin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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