Document Detail


Regulation and autoregulation by lexA protein.
MedLine Citation:
PMID:  6814502     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The lexA protein represses many genes in E. coli. When the cell's DNA is damaged, lexA protein is inactivated and these genes are induced. Three aspects of lexA protein's repressor function are reviewed: how it regulates genes of the SOS response, how it regulates its own synthesis, and how it recognizes its operator sites. Recent studies of lexA protein's repressor function have suggested that the concentration of intact lexA protein after induction may determine the detailed control of the SOS response.
Authors:
R Brent
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Biochimie     Volume:  64     ISSN:  0300-9084     ISO Abbreviation:  Biochimie     Publication Date:    1982 Aug-Sep
Date Detail:
Created Date:  1983-01-27     Completed Date:  1983-01-27     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  1264604     Medline TA:  Biochimie     Country:  FRANCE    
Other Details:
Languages:  eng     Pagination:  565-9     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Bacterial Proteins / genetics*
DNA Repair*
Escherichia coli / genetics*
Genes, Bacterial*
Genes, Regulator
Mutation
Protein Binding
Serine Endopeptidases*
Transcription, Genetic
Chemical
Reg. No./Substance:
0/Bacterial Proteins; 0/LexA protein, Bacteria; EC 3.4.21.-/Serine Endopeptidases

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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