| Regulation of fatty acid metabolism by cell autonomous circadian clocks: time to fatten up on information? | |
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MedLine Citation:
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PMID: 21296875 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Molecular, cellular, and animal-based studies have recently exposed circadian clocks as critical regulators of energy balance. Invariably, mouse models of genetically manipulated circadian clock components display features indicative of altered lipid/fatty acid metabolism, including differential adiposity and circulating lipids. The purpose of this minireview is to provide a comprehensive summary of current knowledge regarding the regulation of fatty acid metabolism by distinct cell autonomous circadian clocks. The implications of these recent findings for cardiometabolic disease and human health are discussed. |
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Authors:
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Molly S Bray; Martin E Young |
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Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review Date: 2011-02-04 |
Journal Detail:
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Title: The Journal of biological chemistry Volume: 286 ISSN: 1083-351X ISO Abbreviation: J. Biol. Chem. Publication Date: 2011 Apr |
Date Detail:
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Created Date: 2011-04-04 Completed Date: 2011-07-19 Revised Date: 2012-04-09 |
Medline Journal Info:
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Nlm Unique ID: 2985121R Medline TA: J Biol Chem Country: United States |
Other Details:
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Languages: eng Pagination: 11883-9 Citation Subset: IM |
Affiliation:
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Department of Epidemiology, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Circadian Clocks / genetics, physiology* Fatty Acids / metabolism* Humans Lipid Metabolism / genetics, physiology* |
| Grant Support | |
ID/Acronym/Agency:
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HL-074259/HL/NHLBI NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Fatty Acids |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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