Document Detail

Regulation of BCR signaling.
MedLine Citation:
PMID:  21195477     Owner:  NLM     Status:  Publisher    
B cells and antibodies are important elements of acquired humoral immunity in the fight against various pathogens, and signals through the B cell receptor (BCR) are crucial for the development, activation and differentiation of B cells. Our laboratory has focused on understanding the molecular mechanisms of BCR-mediated signaling cascades that regulate these processes in B cells. In this review, I will briefly present our studies that have clarified the molecular components of signaling cascades, mainly focusing on data using DT40 B cells and their genetic variants.
Tomohiro Kurosaki
Related Documents :
2168017 - Polyomavirus-based shuttle vectors for studying mechanisms of mutagenesis in rodent cells.
8660947 - Roles of xpg and xpf/ercc1 endonucleases in uv-induced immunostaining of pcna in fibrob...
17698617 - A novel role for protein kinase cdelta-mediated phosphorylation of acid sphingomyelinas...
1177957 - A comparison of chromosomal radiosensitivities of somatic cells of mouse and man.
22383647 - Single-molecule imaging of stochastic signaling events in living cells.
8695867 - Opposite effects of tumor necrosis factor alpha on the sphingomyelin-ceramide pathway i...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2010-12-30
Journal Detail:
Title:  Molecular immunology     Volume:  -     ISSN:  1872-9142     ISO Abbreviation:  -     Publication Date:  2010 Dec 
Date Detail:
Created Date:  2011-1-3     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7905289     Medline TA:  Mol Immunol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2010 Elsevier Ltd. All rights reserved.
Laboratory of Lymphocyte Differentiation, WPI Immunology Frontier Research Center, Osaka University, 3-1 Yamadaoka, Suita, Osaka 565-0871, Japan; Laboratory for Lymphocyte Differentiation, RIKEN Research Center for Allergy and Immunology, 1-7-22, Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa 230-0045, Japan.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Elsevier trophoblast research award lecture: The multifaceted role of Nodal signaling during mammali...
Next Document:  L2pB1: a new player in autoimmunity.