Document Detail


Regulating myocardial blood flow in health and disease.
MedLine Citation:
PMID:  19236827     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Regulating myocardial blood flow in health and disease is a complex, multifaceted process. The objective of this article is to outline for the practicing clinician a basic set of principles necessary for understanding important control mechanisms operative under normal physiologic conditions and in selected common disease states. Classical and newer insights into the process of myocardial blood flow regulation are reviewed. An improved understanding of these control mechanisms will enhance the clinician's ability to diagnose and treat abnormalities of the coronary circulation associated with such common clinical conditions as ischemic heart disease, diabetes, dyslipidemia, hypertension, and congestive heart failure.
Authors:
Henry Gewirtz
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Current cardiology reports     Volume:  11     ISSN:  1534-3170     ISO Abbreviation:  Curr Cardiol Rep     Publication Date:  2009 Mar 
Date Detail:
Created Date:  2009-02-24     Completed Date:  2010-01-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100888969     Medline TA:  Curr Cardiol Rep     Country:  United States    
Other Details:
Languages:  eng     Pagination:  117-24     Citation Subset:  IM    
Affiliation:
Nuclear Cardiology/Yawkey 5E, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA. hgewirtz@partners.org
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MeSH Terms
Descriptor/Qualifier:
Cardiovascular Diseases / physiopathology*
Collateral Circulation*
Coronary Circulation*
Heart Failure / physiopathology
Hemodynamics
Humans
Hypertension / physiopathology
Myocardial Ischemia / physiopathology
Myocardium* / metabolism
Oxygen Consumption*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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