Document Detail

Regulating the introduction of new chemicals under section 5 of TSCA: improving the efficiency of the process and reducing potential injury in the workplace through the use of operational MSDS and exposure limits.
MedLine Citation:
PMID:  1669965     Owner:  NLM     Status:  MEDLINE    
The Toxic Substances Control Act (TSCA) authorizes the EPA to take appropriate actions to ensure that new and existing chemicals do not pose "unreasonable risk" to health or the environment. Section 2(b)(3) of the Act directs the Agency to accomplish this objective in a manner that does "not impede unduly or create unnecessary economic barriers to technological innovation." In recent years, critics have felt that the EPA has failed to achieve these primary goals of TSCA. This paper considers some of the reasons for this criticism and advocates an alternate approach of exposure limits and operationally sufficient controls to assist in achieving these goals. An illustration of how this alternate approach might work under practical conditions is presented, using as an example a new chemical substance from the class of acrylate monomers. These concepts and risk assessments provide data for a better design of future studies according to good laboratory practice and quality assurance.
I Rosenthal; M A Jayjock; R L Keener; J E Plamondon
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Quality assurance (San Diego, Calif.)     Volume:  1     ISSN:  1052-9411     ISO Abbreviation:  Qual Assur     Publication Date:  1991 Oct 
Date Detail:
Created Date:  1994-05-04     Completed Date:  1994-05-04     Revised Date:  2000-12-18    
Medline Journal Info:
Nlm Unique ID:  9214530     Medline TA:  Qual Assur     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  10-30     Citation Subset:  IM    
Safety Health and Environmental Affairs Department, Rohm and Haas Company, Bristol, PA.
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MeSH Terms
Chemical Industry / legislation & jurisprudence*
Environmental Monitoring / standards
Environmental Pollution / legislation & jurisprudence*,  prevention & control
Hazardous Substances*
Maximum Allowable Concentration
Occupational Exposure / legislation & jurisprudence*,  prevention & control
Risk Factors
United States
United States Environmental Protection Agency
Reg. No./Substance:
0/Hazardous Substances

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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