Document Detail


Regular heartbeat dynamics are associated with cardiac health.
MedLine Citation:
PMID:  16973939     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The human heartbeat series is more variable and, hence, more complex in healthy subjects than in congestive heart failure (CHF) patients. However, little is known about the complexity of the heart rate variations on a beat-to-beat basis. We present an analysis based on symbolic dynamics that focuses on the dynamic features of such beat-to-beat variations on a small time scale. The sequence of acceleration and deceleration of eight successive heartbeats is represented by a binary sequence consisting of ones and zeros. The regularity of such binary patterns is quantified using approximate entropy (ApEn). Holter electrocardiograms from 30 healthy subjects, 15 patients with CHF, and their surrogate data were analyzed with respect to the regularity of such binary sequences. The results are compared with spectral analysis and ApEn of heart rate variability. Counterintuitively, healthy subjects show a large amount of regular beat-to-beat patterns in addition to a considerable amount of irregular patterns. CHF patients show a predominance of one regular beat-to-beat pattern (alternation of acceleration and deceleration), as well as some irregular patterns similar to the patterns observed in the surrogate data. In healthy subjects, regular beat-to-beat patterns reflect the physiological adaptation to different activities, i.e., sympathetic modulation, whereas irregular patterns may arise from parasympathetic modulation. The patterns observed in CHF patients indicate a largely reduced influence of the autonomic nervous system. In conclusion, analysis of short beat-to-beat patterns with respect to regularity leads to a considerable increase of information compared with spectral analysis or ApEn of heart-rate variations.
Authors:
Dirk Cysarz; Silke Lange; Peter F Matthiessen; Peter van Leeuwen
Related Documents :
20702919 - Photoplethysmography pulse rate variability as a surrogate measurement of heart rate va...
10996189 - Breathing frequencies of northern elephant seals at sea and on land revealed by heart r...
24627459 - Noise and adaptation in multistable perception: noise drives when to switch, adaptation...
2810469 - Ritual and free-throw shooting in basketball.
17520359 - Capture of activation during ventricular arrhythmia using distributed stimulation.
2283529 - Spectral analysis of tremor: understanding the results.
22722899 - Monopolar intracochlear pulse trains selectively activate the inferior colliculus.
22634759 - Transposase-derived proteins fhy3/far1 interact with phytochrome-interacting factor1 to...
20929199 - Thiolated dextran-coated gold nanorods for photothermal ablation of inflammatory macrop...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2006-09-14
Journal Detail:
Title:  American journal of physiology. Regulatory, integrative and comparative physiology     Volume:  292     ISSN:  0363-6119     ISO Abbreviation:  Am. J. Physiol. Regul. Integr. Comp. Physiol.     Publication Date:  2007 Jan 
Date Detail:
Created Date:  2007-01-01     Completed Date:  2007-02-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100901230     Medline TA:  Am J Physiol Regul Integr Comp Physiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  R368-72     Citation Subset:  IM    
Affiliation:
Medical Theory and Complementary Medicine, University of Witten/Herdecke, Gerhard-Kienle-Weg 4, D-58313 Herdecke, Germany. d.cysarz@rhythmen.de
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Algorithms
Coronary Disease / physiopathology
Data Interpretation, Statistical
Electrocardiography, Ambulatory
Entropy
Female
Health*
Heart / physiology*
Heart Rate / physiology*
Humans
Male
Middle Aged

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Dexamethasone-induced protein degradation in cultured myotubes is p300/HAT dependent.
Next Document:  Combined prenatal and postnatal protein restriction influences adult kidney structure, function, and...