| Regression of a prolactin-secreting pituitary tumor during long-term treatment with bromocriptine. | |
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MedLine Citation:
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PMID: 729834 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A nulliparous woman with 12 years of amenorrhea, galactorrhea, and hyperprolactinemia and radiologic evidence of a pituitary macroadenoma was treated with large doses of bromocriptine. During treatment the greatly increased prolactin levels normalized and ovulatory menstrual cycles were regained after 48 weeks of treatment. A transsphenoidal surgical exploration of the pituitary fossa was performed after 27 months of treatment. The findings at surgery suggested that regression of the pituitary adenoma had occurred during the prolonged treatment with bromocriptine. After discontinuation of the therapy, the patient continued to ovulate and subsequently conceived. |
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Authors:
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S J Nillius; T Bergh; P O Lundberg; J Stahle; L Wide |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Fertility and sterility Volume: 30 ISSN: 0015-0282 ISO Abbreviation: Fertil. Steril. Publication Date: 1978 Dec |
Date Detail:
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Created Date: 1979-03-13 Completed Date: 1979-03-13 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0372772 Medline TA: Fertil Steril Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 710-2 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adenoma
/
complications,
drug therapy*,
secretion Adult Amenorrhea / etiology Bromocriptine / therapeutic use* Female Galactorrhea / etiology Humans Pituitary Neoplasms / complications, drug therapy*, secretion Pregnancy Prolactin / blood |
| Chemical | |
Reg. No./Substance:
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25614-03-3/Bromocriptine; 9002-62-4/Prolactin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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