Document Detail


Regression of giant bullous emphysema.
MedLine Citation:
PMID:  20046002     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Spontaneous resolution of bulla associated with infection or tumor is occasionally observed. However, resolution of progressively enlarging giant bullous emphysema (GBE) after medical therapy has not been reported. A 51-year-old man smoker with GBE on the right lung was referred to Samsung Medical Center for the consideration of bullectomy. A review of his medical records revealed that right-side bullous emphysema had been detected 4 years previously and it had progressively enlarged with a concomitant deterioration of lung function. Although he had a history of chronic asthma, he had never been treated on a regular basis. After combination therapy, including regular tiopropium, a salmeterol/flucatisone inhaler, a salbutamol inhaler as needed, and oral theophylline therapy, right side bulla showed marked regression. This regression of bulla was associated with an improved forced expiratory volume in one second and normalization of residual volume. This case serves as a reminder to clinicians that medical treatment for underlying diseases should precede surgical consideration in patients with GBE.
Authors:
Hye Yun Park; Seong Yong Lim; Hye Kyeong Park; So Young Park; Tae Sung Kim; Gee Young Suh
Publication Detail:
Type:  Case Reports; Journal Article     Date:  2010-01-01
Journal Detail:
Title:  Internal medicine (Tokyo, Japan)     Volume:  49     ISSN:  1349-7235     ISO Abbreviation:  Intern. Med.     Publication Date:  2010  
Date Detail:
Created Date:  2010-01-04     Completed Date:  2010-04-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9204241     Medline TA:  Intern Med     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  55-7     Citation Subset:  IM    
Affiliation:
Division of Pulmonary and Critical Care Medicine, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
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MeSH Terms
Descriptor/Qualifier:
Administration, Inhalation
Albuterol / administration & dosage*,  analogs & derivatives*
Asthma / complications,  drug therapy
Bronchodilator Agents / administration & dosage*
Drug Therapy, Combination
Humans
Lung, Hyperlucent / complications,  drug therapy*,  radiography
Male
Middle Aged
Remission Induction
Theophylline / administration & dosage
Tomography, X-Ray Computed
Chemical
Reg. No./Substance:
0/Bronchodilator Agents; 18559-94-9/Albuterol; 58-55-9/Theophylline; 89365-50-4/salmeterol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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