| Regional parasite density in the skin of dogs with symptomatic canine leishmaniosis. | |
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MedLine Citation:
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PMID: 17610487 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In canine leishmaniosis, the parasitic density of the skin may be important for the infection of sandflies, and increased accumulation of inflammatory cells infected with Leishmania is believed to occur in dermal areas subjected to mechanical trauma. Parasite density and inflammatory responses in the upper and lower dermis of three body sites: flank (control site), dorsal muzzle (sandfly feeding site), and footpads (mechanical stress sites) were thus investigated in 15 dogs with symptomatic leishmaniosis. Parasite density did not differ between the control and tested sites or between the upper and lower dermis, apart from the footpads where it was higher in the upper dermis, and there was no correlation with severity of the macroscopic lesions or inflammatory infiltrate, except for the lower footpad dermis. No selective accumulation of the parasite in the muzzle that would favour its transmission to sandflies occurred, and the mechanical stress imposed on the footpads was not associated with increased parasitic density, or with inflammatory infiltrate. |
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Authors:
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Manolis N Saridomichelakis; Alexander F Koutinas; Thierry Olivry; Stan M Dunston; Rania Farmaki; Christos K Koutinas; Theodoros Petanides |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Veterinary dermatology Volume: 18 ISSN: 0959-4493 ISO Abbreviation: Vet. Dermatol. Publication Date: 2007 Aug |
Date Detail:
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Created Date: 2007-07-05 Completed Date: 2007-08-14 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9426187 Medline TA: Vet Dermatol Country: England |
Other Details:
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Languages: eng Pagination: 227-33 Citation Subset: IM |
Affiliation:
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Companion Animal Clinic, Faculty of Veterinary Medicine, Aristotle University of Thessaloniki, Greece. msarido@vet.uth.gr |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Case-Control Studies Dog Diseases / parasitology*, pathology Dogs Female Leishmania / isolation & purification, pathogenicity Leishmaniasis, Cutaneous / parasitology, veterinary* Male Severity of Illness Index |
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