Document Detail


Regional mapping of the Rowett nude gene (RONU) to rat chromosome 10q24-->q32 by localizing linked SYB2 and GH loci.
MedLine Citation:
PMID:  8467707     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The Rowett nude gene (RONU) has been mapped on rat chromosome (Chr) 10 by linkage analysis using (ACI x F344/N-RONU/RONU)F1 x F344/N-RONU/RONU backcross progeny. The gene order on the chromosome was RR92- (16.1 cM) - RR24 - (17.9 cM) - MYHSE (myosin heavy chain, embryonic) - (1.0 cM) - SYB2 (synaptobrevin 2) - (1.0 cM) - SHBG (sex hormone-binding globulin) - (4.0 cM) - RONU (Rowett nude) - (29.0 cM) - AEP (anion exchange protein), PPY (pancreatic polypeptide) - (3.0 cM) - ACE (angiotensin I converting enzyme), GH (growth hormone). The RONU locus was localized to 10q24-->q32 by fluorescence in situ hybridization of the closely linked SYB2 and loosely linked GH loci on the opposite side. Conserved linkage of homologous loci mapped to rat Chr 10 and mouse Chr 11 supports the hypothesis that the RONU locus is a rat homolog of the mouse nu locus.
Authors:
T Kuramoto; T Serikawa; N Hayasaka; M Mori; J Yamada
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Cytogenetics and cell genetics     Volume:  63     ISSN:  0301-0171     ISO Abbreviation:  Cytogenet. Cell Genet.     Publication Date:  1993  
Date Detail:
Created Date:  1993-05-13     Completed Date:  1993-05-13     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  0367735     Medline TA:  Cytogenet Cell Genet     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  107-10     Citation Subset:  IM    
Affiliation:
Institute of Laboratory Animals, Faculty of Medicine, Kyoto University, Japan.
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MeSH Terms
Descriptor/Qualifier:
Animals
Chromosome Mapping*
Genetic Markers
Growth Hormone / genetics
Humans
In Situ Hybridization, Fluorescence
Linkage (Genetics)
Membrane Proteins / genetics
Mice
Nerve Tissue Proteins / genetics
Polymorphism, Genetic
R-SNARE Proteins
Rats
Rats, Inbred F344
Rats, Nude / genetics*
Chemical
Reg. No./Substance:
0/Genetic Markers; 0/Membrane Proteins; 0/Nerve Tissue Proteins; 0/R-SNARE Proteins; 9002-72-6/Growth Hormone

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