| Regional intrapulmonary gas distribution in awake and anesthetized-paralyzed man. | |
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MedLine Citation:
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PMID: 264858 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Intrapulmonary distribution of ventilation/unit lung volume was studied in 28 volunteers in the sitting, supine, or right lateral decubitus position, either awake or anesthetized-paralyzed and mechanically ventilated. We found significant differences between the awake state and anesthesia-paralysis with mechanical ventilation in 1) intrapulmonary gas distribution, and 2) the vertical gradient of regional functional residual capacities for the subjects in the lateral decubitus position, but not for those in the sitting and supine positions. The effect of increasing the tidal volume on distribution of ventilation was significantly different 1) between the three body positions for a given state, and 2) between the two states for a given body position. The data suggest thoracoabdominal mechanics are different in the three body positions and that anesthesia-paralysis and mechanical ventilation may cause a different pattern of expansion of the respiratory system than spontaneous breathing in the awake state. |
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Authors:
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K Rehder; A D Sessler; J R Rodarte |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Journal of applied physiology: respiratory, environmental and exercise physiology Volume: 42 ISSN: 0161-7567 ISO Abbreviation: J Appl Physiol Publication Date: 1977 Mar |
Date Detail:
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Created Date: 1977-04-30 Completed Date: 1977-04-30 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7801242 Medline TA: J Appl Physiol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 391-402 Citation Subset: IM |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Anesthesia* Functional Residual Capacity Humans Male Paralysis / chemically induced, physiopathology* Posture* Pulmonary Diffusing Capacity Respiration* Tidal Volume Ventilators, Mechanical Wakefulness / physiology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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