Document Detail


Regional histaminergic potencies in rabbit systemic circulation.
MedLine Citation:
PMID:  1936898     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
1. Regional activity of histamine was studied in various rabbit arteries, including segments of the aorta, aortic branches, branchout regions and arteries to fore and hind limbs by dose-response experiments. 2. Local histaminergic potencies were found to be heterogenceous. Circular and longitudinal smooth muscle responsivity in the aorta increased in the distal direction; aortic branches have their own histaminergic response characteristics beginning from their branchouts. Paired arteries (right and left subclavia, renal and iliac) possess matching histaminergic activities. 3. The observed characteristics of the responses suggest predetermined distribution of histaminergic activities along systemic circulation which may be regulatory in the distribution of blood.
Authors:
H Gürbüz; H O Onaran; T A Bökesoy
Related Documents :
9400378 - Nitric oxide-independent dilation of conductance coronary arteries to acetylcholine in ...
2923228 - Adrenergic control of intrarenal arteries of rabbits.
11471068 - Possible role of nitric oxide and arachidonic acid pathways in hypoxia-induced contract...
9234658 - Heterogeneity in the vasorelaxing effect of nicorandil on dog epicardial coronary arter...
15877728 - Chronic sickle cell lung disease: new insights into the diagnosis, pathogenesis and tre...
21234918 - Transcatheter occlusion of the patent ductus arteriosus in infants - experimental testi...
Publication Detail:
Type:  In Vitro; Journal Article    
Journal Detail:
Title:  General pharmacology     Volume:  22     ISSN:  0306-3623     ISO Abbreviation:  Gen. Pharmacol.     Publication Date:  1991  
Date Detail:
Created Date:  1991-12-06     Completed Date:  1991-12-06     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7602417     Medline TA:  Gen Pharmacol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  659-61     Citation Subset:  IM    
Affiliation:
Department of Pharmacology, Faculty of Medicine, Ankara University, Sihhiye, Turkey.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Animals
Arteries / drug effects*
Drug Resistance
Female
Histamine / pharmacology*
Male
Rabbits
Receptors, Histamine / drug effects,  physiology
Vasoconstriction / drug effects
Chemical
Reg. No./Substance:
0/Receptors, Histamine; 51-45-6/Histamine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Effect of progesterone on norepinephrine release from mouse adrenergic terminals in vitro.
Next Document:  Chronic administration of nicotine fails to alter the MPTP-induced neurotoxicity in mice.