| Regional differences for the D-amino acid oxidase-catalysed oxidation of D-methionine in chicken small intestine. | |
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MedLine Citation:
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PMID: 1351830 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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1. Enzymic oxidation of D-[1-14C]methionine (D-met) to 2-keto-4-methylthiobutanoate (KMB) has been determined using 100,000 g supernatants prepared from chicken tissue homogenates. 2. The small intestinal mucosa contains substantial oxidative activity towards D-met, which represents about one-half and one-tenth the hepatic and renal activity, respectively. 3. KMB is poorly decarboxylated and rather transaminated to L-met. 4. The specific activity for D-met oxidation in the duodenal mucosa is 1.5- and 4.0-fold than in the jejunal and ileal mucosa, respectively. 5. The intestinal D-met-oxidizing activity is dramatically altered by the D-amino acid oxidase specific inhibitor benzoate. |
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Authors:
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P Brachet; A Puigserver |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Comparative biochemistry and physiology. B, Comparative biochemistry Volume: 101 ISSN: 0305-0491 ISO Abbreviation: Comp. Biochem. Physiol., B Publication Date: 1992 Apr |
Date Detail:
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Created Date: 1992-07-30 Completed Date: 1992-07-30 Revised Date: 2003-11-14 |
Medline Journal Info:
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Nlm Unique ID: 2984730R Medline TA: Comp Biochem Physiol B Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 509-11 Citation Subset: IM |
Affiliation:
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I.N.R.A., Faculté des Sciences Pharmaceutiques et Biologiques, Paris, France. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Catalysis Chickens D-Amino-Acid Oxidase / metabolism* Duodenum / metabolism Intestinal Mucosa / metabolism Intestine, Small / metabolism* Jejunum / metabolism Kidney / metabolism Liver / metabolism Methionine / metabolism* Oxidation-Reduction |
| Chemical | |
Reg. No./Substance:
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63-68-3/Methionine; EC 1.4.3.3/D-Amino-Acid Oxidase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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